Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of MOPd(PO) (M = Sn, Pb).

08:00 EDT 14th August 2019 | BioPortfolio

Summary of "Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of MOPd(PO) (M = Sn, Pb)."

The first two examples of polyoxopalladates(II) (POPs) containing tetravalent metal ion guests, [MOPd(PO)] (M = Sn, Pb), have been prepared and structurally characterized in the solid state, solution, and gas phase. The interactions of the metal ion guests and the palladium-oxo shell were studied by theoretical calculations. The POPs were shown to possess anticancer activity by causing oxidative stress inducing caspase activation and consecutive apoptosis of leukemic cells.


Journal Details

This article was published in the following journal.

Name: Inorganic chemistry
ISSN: 1520-510X


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