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DNA origami nanoplate-based emulsion with designed nanopore function.

08:00 EDT 14th August 2019 | BioPortfolio

Summary of "DNA origami nanoplate-based emulsion with designed nanopore function."

Bio-inspired functional microcapsules have attracted increasing attention in many fields from physical/chemical science to artificial cell engineering. Although the particle-stabilised microcapsules are advantageous for their stability and functionalisation potential, versatile methods for their designable functionalisation are desired to expand their possibilities. This study reports a water-in-oil microdroplet stabilised with amphiphilised DNA origami nanoplates. By utilising DNA nanotechnology, DNA nanoplates were designed as a nanopore device for ion transportation and as an interface stabiliser. Microscopic examination revealed the microcapsule formed by the accumulation of amphiphilic DNA nanoplates at the oil-water interface. Ion current measurements revealed the nanoplate pores functioned as channel to transport ions. These findings provide a general strategy for programmable design of microcapsules to engineer artificial cells and molecular robots.

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This article was published in the following journal.

Name: Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
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