Thermally Induced Reversible Self-Assembly of Apoferritin-Block Copolymer Complexes.

08:00 EDT 14th August 2019 | BioPortfolio

Summary of "Thermally Induced Reversible Self-Assembly of Apoferritin-Block Copolymer Complexes."

Protein cages are interesting building blocks for functional supramolecular assemblies. A multi-responsive system composed of apoferritin and thermo-responsive block copolymers complexed through electrostatic interactions is described here. The polymers are linear chains with cationic and thermo-responsive blocks, and both diblock and triblock copolymers are studied. The apoferritin can be reversibly assembled and disassembled in aqueous solutions by altering the temperature and electrolyte concentration of the solutions. The control over the conditions is straightforward and all the components can be recovered, offering a potential alternative for systems requiring chemical or genetic modification of proteins.


Journal Details

This article was published in the following journal.

Name: Macromolecular rapid communications
ISSN: 1521-3927
Pages: e1900308


DeepDyve research library

PubMed Articles [13086 Associated PubMed Articles listed on BioPortfolio]

ABA-type triblock copolymer micellar system with lower critical solution temperature-type sol-gel transition.

A temperature sensitive sol-gel transition induced by the self-assembly of amphiphilic copolymers and its application in industry have been the objects of increasing study. We demonstrate here a two-s...

Staged Surface Patterning and Self-Assembly of Nanoparticles Functionalized with End-Grafted Block Copolymer Ligands.

Using two orthogonal external stimuli, we achieved programmable "staged" surface patterning and self-assembly of inorganic nanoparticles (NPs). For gold NPs capped with end-grafted poly(styrene-block-...

Controlled Assembly of Block Copolymer Coated Nanoparticles in 2D Arrays.

The defined assembly of nanoparticles (NPs) in polymer matrices is an important prerequisite for next-generation functional materials. A promising approach to control NP positions in polymer matrices ...

Self-assembly of block copolymers during hollow fiber spinning: an in situ small-angle X-ray scattering study.

We investigated the self-assembly of block copolymers during hollow fiber membrane (HFM) fabrication by conducting in situ small angle X-ray scattering (SAXS) and ex situ scanning electron microscopy ...

Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging.

Self-assembly is a powerful tool to organize the elementary molecular units into functional nanostructures, which provide reversible stimulus-responsive systems for a variety of purposes. However, the...

Clinical Trials [5424 Associated Clinical Trials listed on BioPortfolio]

Clinical Investigation to Evaluate the Haemonetics POLFA Modified Sample Needle Assembly With Vacuum Tube Holder

This study evaluates whether whole blood transferred through the new POLFA needle assembly meets supernatant hemoglobin acceptability standards.

Safety Study of Polylactide-Caprolactone-Trimethylenecarbonate Copolymer for Post-Operative Adhesion Prophylaxis

The purpose of this study is to compare adhesion prophylaxis with polylactide-caprolactone-trimethylenecarbonate copolymer to icodextrin 4% in terms of safety, side effects and usability i...

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Copolymer 1 for Relapsing-Remitting Multiple Sclerosis

OBJECTIVES: I. Compare tolerance to and therapeutic impact of copolymer 1, a mixture of synthetic polypeptides, with placebo in patients with relapsing-remitting multiple sclerosis.

The Mechanism of Melanocyte Self-Assembly on Biomaterials and the Functional Analysis

The aim of this study is to survey melanocytes in the ability of self-assembly on biomaterials and functional analysis in vitro. Also, this study may provide a better way for treatment of ...

Investigation of Thermal Injury on Intestinal Permeability in Both Thermal Injury and Healthy Participants

This longitudinal, prospective study aims to establish the magnitude and time course of changes in intestinal permeability; establish the optimal method for assessment of intestinal permea...

Medical and Biotech [MESH] Definitions

Copolymer of divinyl ether and maleic anhydride that acts as an immunostimulant with antineoplastic and anti-infective properties. It is used in combination with other antineoplastic agents.

Interruption of sympathetic pathways, by local injection of an anesthetic agent, at any of four levels: peripheral nerve block, sympathetic ganglion block, extradural block, and subarachnoid block.

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.

Abnormally high temperature intentionally induced in living things regionally or whole body. It is most often induced by radiation (heat waves, infra-red), ultrasound, or drugs.

Gram-negative aerobic rods, isolated from surface water, mud, or thermally polluted lakes or streams. It is pathogenic for man and it has no known soil or animal sources.

Quick Search

DeepDyve research library

Relevant Topic

Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...

Searches Linking to this Article