Synovial fluid erythrophagocytosis: inflammation or drug-induced change?

08:00 EDT 14th August 2019 | BioPortfolio

Summary of "Synovial fluid erythrophagocytosis: inflammation or drug-induced change?"

Erythrophagocytosis (EPC) may be detected on microscopy examination by the presence of erythrocytes in the cytoplasm of phagocytes. This type of phagocytosis is rarely described in the medical literature, including medical textbooks. Recent reports mention EPC in peripheral blood samples in severe cold agglutinin disease; in parvovirus-B19 and Epstein Barr virus associated warm IgM-mediated hemolytic anemia; in incompatible transfusion; in sickle cell disease as well as in paroxysmal cold hemoglobinuria and in potassium chlorate poisoning [1,2]. We report our recent finding of EPC in a synovial fluid specimen. This article is protected by copyright. All rights reserved.


Journal Details

This article was published in the following journal.

Name: Cytopathology : official journal of the British Society for Clinical Cytology
ISSN: 1365-2303


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Medical and Biotech [MESH] Definitions

The clear, viscous fluid secreted by the SYNOVIAL MEMBRANE. It contains mucin, albumin, fat, and mineral salts and serves to lubricate joints.

Non-neoplastic tumor-like lesions at joints, developed from the SYNOVIAL MEMBRANE of a joint through the JOINT CAPSULE into the periarticular tissues. They are filled with SYNOVIAL FLUID with a smooth and translucent appearance. A synovial cyst can develop from any joint, but most commonly at the back of the knee, where it is known as POPLITEAL CYST.

A fluid-filled sac lined with SYNOVIAL MEMBRANE that provides a cushion between bones, tendons and/or muscles around a joint.

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The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.

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