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The search for an inhabited planet, beyond our own, is a driver of planetary exploration in our solar system and beyond. Using information from our own planet to inform search strategies allows for a targeted search. It is, however, worth considering some span in the strategy and in expectation. An inhabited, Earth-like planet is one that would be similar to Earth in ways that extend beyond having biota. To facilitate a comparative cost/risk/benefit analysis of different potential search strategies, we use a metric akin to the Earth-similarity index. The metric extends from zero, for an inhabited planet that is like Earth in all other regards (, zero differences), toward end-member values for planets that differ from Earth but maintain life potential. The analysis shows how finding inhabited planets that do not share other Earth characteristics could improve our ability to assess galactic life potential without a large increase in time-commitment costs. Search strategies that acknowledge the possibility of such planets can minimize the potential of exploration losses (, searching for long durations to reach conclusions that are biased). Discovering such planets could additionally provide a test of the Gaia hypothesis-a test that has proven difficult when using only Earth as a laboratory. Finally, we discuss how an Earth2.0 narrative that has been presented to the public as a search strategy comes with nostalgia-laden baggage that does not best serve exploration.
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European decision support modelling of long-term external doses received in inhabited areas contaminated by a nuclear power plant accident - 1: Initial relative dose rate contributions from different contaminated outdoor surfaces.
Dose prediction tools making use of existing knowledge on the environmental behaviour of radiocontaminants are essential for justification and optimisation of recovery countermeasure strategies for co...
Reproductive sciences have made major contributions to human health, livestock production and environmental management in the past and will continue to do so in future. In collaboration with other dis...
The lichen Buellia frigida was exposed to space and simulated Mars analog conditions in the Biology and Mars Experiment (BIOMEX) project operated outside the International Space Station (ISS) for 1.5 ...
Vortex fiber nulling is a method for spectroscopically characterizing exoplanets at small angular separations, ≲λ/D, from their host star. The starlight is suppressed by creating an optical vortex ...
The most significant processes of arbovirus evolution can be expected to occur in the territories where ticks of different species cohabitate and at the boundaries of virus occurrence, where the proba...
The purpose of this project is to test the efficacy of Planet T1D, a mobile and web-based technology infrastructure specifically designed to (a) enhance youths' type 1 diabetes disease- an...
The purpose of this project is to test the efficacy of Planet K, a mobile and web-based technology infrastructure specifically designed to (a) enhance youths' chronic kidney disease- and t...
This open-label, multicenter study will evaluate the safety and efficacy of RO53 23441 in combination with Avastin (bevacizumab) in patients with recurrent gliob lastoma. In the dose-findi...
The polyglycolic acid (PGA) mesh is a felt-like absorbable suture reinforcing material. The pancreatojejunostomy aimed at reducing POPF is not established at present. We devised a new meth...
The purpose of this clinical trial is to evaluate the ability of various biomarkers measured in serum and/or pleural fluids to estimate the risk of finding cancer in patients with undiagno...
A nonspecific term referring both to the pathologic finding of swelling of distal portions of axons in the brain and to disorders which feature this finding. Neuroaxonal dystrophy is seen in various genetic diseases, vitamin deficiencies, and aging. Infantile neuroaxonal dystrophy is an autosomal recessive disease characterized by arrested psychomotor development at 6 months to 2 years of age, ataxia, brain stem dysfunction, and quadriparesis. Juvenile and adult forms also occur. Pathologic findings include brain atrophy and widespread accumulation of axonal spheroids throughout the neuroaxis, peripheral nerves, and dental pulp. (From Davis & Robertson, Textbook of Neuropathology, 2nd ed, p927)
Therapy by finding a better CLIMATE for health.
The process of finding chemicals for potential therapeutic use.
Techniques for effecting the transition of the respiratory-failure patient from mechanical ventilation to spontaneous ventilation, while meeting the criteria that tidal volume be above a given threshold (greater than 5 ml/kg), respiratory frequency be below a given count (less than 30 breaths/min), and oxygen partial pressure be above a given threshold (PaO2 greater than 50mm Hg). Weaning studies focus on finding methods to monitor and predict the outcome of mechanical ventilator weaning as well as finding ventilatory support techniques which will facilitate successful weaning. Present methods include intermittent mandatory ventilation, intermittent positive pressure ventilation, and mandatory minute volume ventilation.
The deliberate and methodical practice of finding new applications for existing drugs.