Track topics on Twitter Track topics that are important to you
forming hydrogel has emerged as a promising wound dressing recently. As physically crosslinked hydrogels were normally unstable, most forming hydrogels were chemically crosslinked. However, big concerns have remained regarding the slow gelation and the potential toxicity of residual functional groups from crosslinkers or the polymer matrix. Herein, we report a sprayable forming hydrogel composed of poly(N-isopropylacrylamide--n-butylacrylate) -poly(ethylene glycol)- poly(N-isopropylacrylamide--n-butylacrylate) (P(NIPAM--nBA)-PEG-P(NIPAM--nBA), which denoted PEP) copolymer and silver nanoparticles decorated reduced graphene oxide nanosheets (Ag@rGO, which denoted AG) in response to the skin temperature. This thermo-responsive hydrogel exhibits intriguing sol-gel irreversibility at low temperatures for the stable dressing on wound, which is attributed to the inorganic/polymeric dual-network and abundant coordination interactions between Ag@rGO nanosheets and PNIPAM. The biocompatibility and antibacterial ability against methicillin-resistant () of this PEP-AG hydrogel wound dressing are confirmed and , which could transparently promote the healing of a infectious skin defect.
This article was published in the following journal.
Name: ACS nano
Cellulose nanofibrils (CNFs) have been widely used as the reinforcing agent. However, there is still a challenge to control the mechanical properties of CNFs-reinforced hydrogels by changing the envir...
With increasing attention paid to smart materials, self-healing hydrogels with thermo-responses have been greatly developed in the past several years. At the same time, fluorescent or light emitting p...
Blindness and vision impairment are major global health problems. Effective ophthalmic drug delivery poses a significant challenge because of protective physiological barriers and various biological c...
A supramolecular hybrid hydrogel displaying a wide array of dynamic physical properties along with enhanced in vivo stem cell retention has been developed. The key strategy is facilely polymerizing bi...
Facile design and development of photoluminescent graphene quantum dots grafted dextran/glycol-polymeric hydrogel for thermoresponsive triggered delivery of buprenorphine on pain management in tissue implantation.
A novel nano-formulations of biocompatible, biodegradable and thermo-responsive graphene quantum dots (GQDs) loaded dextran/poly(N-isopropylacrylamide) (Dex/PNIPAM) copolymeric matrix was synthesized ...
This study proposes to evaluate the potential of leg thermotherapy as a non-pharmacological intervention that could improve the mobility and exercise tolerance of patients with intermitten...
Corneal damage in critically ill patients is common. There are currently two popular methods of treatment in the UK; hydrogel dressings and lubricating ointment. We propose to randomise pa...
The aim of this non-dispensing fitting study is to evaluate the subjective comfort, lens handling, lens fitting characteristics and visual acuity of different hydrogel lens designs versus ...
The purpose of this study is to determine whether using Taclonex ointment under a hydrogel patch is more effective than using the ointment alone in treating psoriasis. Taclonex ointment is...
This small feasibility study will evaluate the use of hydrogel electrode pads (rather than tap water baths) to deliver iontophoresis treatment using a traditional iontophoresis device. Par...
Non-susceptibility of a microbe to the action of METHICILLIN, a semi-synthetic penicillin derivative.
A strain of Staphylococcus aureus that is non-susceptible to the action of METHICILLIN. The mechanism of resistance usually involves modification of normal or the presence of acquired PENICILLIN BINDING PROTEINS.
A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)
A network of cross-linked hydrophilic macromolecules used in biomedical applications.
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...
Complementary and Alternative Medicine
Alternative medicine are whole medical systems that did not fit with conventional medicine as they have completely different philosophies and ideas on the causes of disease, methods of diagnosis and approaches to treatment. Although often overlapping, co...
Acne Dermatology Eczema Psoriasis Wound Care Dermatology is the medical specialty concerned with the diagnosis and treatment of skin disorders (Oxford Medical Dictionary). As well as studying how the skin works, dermatology covers...