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Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum Disorders.

08:00 EDT 31st August 2019 | BioPortfolio

Summary of "Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum Disorders."

There is growing evidence of altered connectivity in autism spectrum disorders (ASD) between the cerebellum and cortex. Three intrinsic connectivity networks (ICNs) are especially important to cognitive processing in
ASD:
the default mode network (DMN), executive control network (ECN), and salience networks (SNs). The goal of this study was to compare resting-state functional connectivity between the cerebellum and the DMN, ECN, and SN in ASD and typically developing children (n = 74, ages 7-12 years). Children with ASD showed stronger connectivity between the ventral DMN and left cerebellar lobules I-IV. No meaningful relationships were observed between ICN-cerebellar functional connectivity and ASD symptoms. These results suggest that the cerebellum contributes to altered network connectivity in ASD.

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This article was published in the following journal.

Name: Journal of autism and developmental disorders
ISSN: 1573-3432
Pages:

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A childhood disorder predominately affecting boys and similar to autism (AUTISTIC DISORDER). It is characterized by severe, sustained, clinically significant impairment of social interaction, and restricted repetitive and stereotyped patterns of behavior. In contrast to autism, there are no clinically significant delays in language or cognitive development. (From DSM-IV)

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