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The presence of S-sulfonated transthyretin in commercial human serum albumin solutions: Potential contribution to neuropathy.

08:00 EDT 31st August 2019 | BioPortfolio

Summary of "The presence of S-sulfonated transthyretin in commercial human serum albumin solutions: Potential contribution to neuropathy."

Commercial solutions of human serum albumin (HSA) are administered to critically ill patients for the treatment of shock, restoration of blood volume, and the acute management of burns. Previously, conflicting results on the effects of HSA administration have been reported varying from a favorable increase in total plasma antioxidant capacity to a higher mortality rate in traumatic brain injury (TBI) patients. These results could be partially explained due to the known heterogeneity of HSA solutions. We report the discovery of S-sulfonated human transthyretin (hTTR) in HSA solutions.

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This article was published in the following journal.

Name: Clinica chimica acta; international journal of clinical chemistry
ISSN: 1873-3492
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