NOX4 activation is involved in ROS-dependent Jurkat T cell death induced by Entamoeba histolytica.

08:00 EDT 10th September 2019 | BioPortfolio

Summary of "NOX4 activation is involved in ROS-dependent Jurkat T cell death induced by Entamoeba histolytica."

Entamoeba histolytica can induce host cell death through induction of various intracellular signaling pathways. The responses triggered by E. histolytica are closely associated with tissue pathogenesis and immune evasion. Although E. histolytica can induce Reactive Oxygen Species (ROS) in host cells, which NADPH oxidase (NOX) isoform contributes to amoeba-triggered Jurkat T cell death is unclear. In this study, we investigated the signaling role of NOX4-derived ROS in E. histolytica-induced Jurkat T cell death process.


Journal Details

This article was published in the following journal.

Name: Parasite immunology
ISSN: 1365-3024
Pages: e12670


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