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Association between Deep Gray Matter Changes and Neurocognitive Function in Mild Cognitive Impairment and Alzheimer's Disease: A Tensor-Based Morphometric MRI Study.

08:00 EDT 12th September 2019 | BioPortfolio

Summary of "Association between Deep Gray Matter Changes and Neurocognitive Function in Mild Cognitive Impairment and Alzheimer's Disease: A Tensor-Based Morphometric MRI Study."

Atrophy of the deep gray matter (DGM) has been associated with a risk of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) and the degree of cognitive impairment. However, specific knowledge of the associations between degenerative DGM changes and neurocognitive functions remains limited.

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This article was published in the following journal.

Name: Dementia and geriatric cognitive disorders
ISSN: 1421-9824
Pages: 1-11

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Medical and Biotech [MESH] Definitions

Striped gray and white matter consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the thalamus in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The white matter is the internal capsule.

A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.

Central gray matter surrounding the cerebral aqueduct in the mesencephalon. Physiologically it is probably involved in rage reactions, the lordosis reflex, feeding responses, bladder tonus, and pain.

The region of CENTRAL NERVOUS SYSTEM that appears lighter in color than the other type, GRAY MATTER. It mainly consists of MYELINATED NERVE FIBERS and contains few neuronal cell bodies or DENDRITES.

Region of CENTRAL NERVOUS SYSTEM that appears darker in color than the other type, WHITE MATTER. It is composed of neuronal CELL BODIES; NEUROPIL; GLIAL CELLS and CAPILLARIES but few MYELINATED NERVE FIBERS.

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