Nanosized titanium dioxide UV filter increases mixture toxicity when combined with parabens.

08:00 EDT 9th September 2019 | BioPortfolio

Summary of "Nanosized titanium dioxide UV filter increases mixture toxicity when combined with parabens."

To address the concern about the environmental impact of engineered nanoparticles frequently used in the recently marketed personal care and hygiene products (PCPs), we conducted a toxicity assessment and determined the EC values of the nanosized inorganic UV filter TiO (nano-TiO), as well as those of the organic UV filter oxybenzone (BP3) and three parabens (methyl, propyl, and benzylparaben) present in most PCPs formulation. The bioassays were carried out through standardized toxicity bioassays on two environmentally relevant aquatic species i.e. Daphnia magna and Phaeodactylum tricornutum. For nano-TiO 48 h EC on D. magna was 3.09 mgL and for parabens ranged from 32.52 to 1.35 mgL. The two most toxic compounds on D. magna, nano-TiO and benzylparaben (BzP), were further tested with the algae. For nano-TiO 72 h EC value was 2.27 mgL and for BzP it was 10.61 mgL. In addition, D. magna was exposed to selected binary mixtures of the target compounds i.e. nano-TiO+BP3, nano-TiO+BzP and BP3+BzP On the endpoint of 48 h, a synergistic action was observed for nano-TiO+BP3 and nano-TiO+BzP, but an antagonistic effect occurred in the mixture BP3+BzP. These findings suggest that nano-TiO can increase the toxicity of the mixture when combined with other compounds.


Journal Details

This article was published in the following journal.

Name: Ecotoxicology and environmental safety
ISSN: 1090-2414
Pages: 109565


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