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Polarity during tissue repair, a multiscale problem.

08:00 EDT 9th September 2019 | BioPortfolio

Summary of "Polarity during tissue repair, a multiscale problem."

Tissue repair is essential for all organisms, as it protects the integrity and function of tissues and prevents infections and diseases. It takes place at multiple scales, from macroscopic to microscopic levels. Most mechanisms driving tissue repair rely on the correct polarisation of collective cell behaviours, such as migration and proliferation, and polarisation of cytoskeletal and junctional components. Furthermore, re-establishment and maintenance of cell polarity are fundamental for a tissue to be fully repaired and for withstanding mechanical stress during homeostasis and repair. Recent evidence highlights an important role for the interplay between cell polarity and tissue mechanics that are critical in tissue repair.

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This article was published in the following journal.

Name: Current opinion in cell biology
ISSN: 1879-0410
Pages: 31-36

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