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Suppression of aspirin-mediated eosinophil activation by prostaglandin E: Relevance to aspirin/NSAID hypersensitivity.

08:00 EDT 9th September 2019 | BioPortfolio

Summary of "Suppression of aspirin-mediated eosinophil activation by prostaglandin E: Relevance to aspirin/NSAID hypersensitivity."

Aspirin-exacerbated respiratory disease (AERD) is characterized by severe, sometimes life-threatening reactions to non-steroidal anti-inflammatory drugs(NSAID). Mechanisms driving the disease include overproduction of leukotrienes and loss of anti-inflammatory prostaglandin E2 (PGE2) production. Many cell types contribute to the disease, however eosinophils are markedly elevated and are important drivers of pathology.

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This article was published in the following journal.

Name: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
ISSN: 1534-4436
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Medical and Biotech [MESH] Definitions

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A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.

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Respiratory
Asthma COPD Cystic Fibrosis Pneumonia Pulmonary Medicine Respiratory Respiratory tract infections (RTIs) are any infection of the sinuses, throat, airways or lungs.  They're usually caused by viruses, but they can also ...


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