Track topics on Twitter Track topics that are important to you
The brain mechanisms of working memory (WM) training in humans remain unclear. Here we examined how WM updating training modulates a cascade of event-related potentials (ERPs) elicited at different processing stages. We hypothesized that WM updating training results to decreases in the early responses reflecting stimulus selection and response preparation, and increases the late slow responses reflecting maintenance of to-be-remembered materials. Healthy adults were randomized to a WM updating group that trained an adaptive dual n-back task (n=20), and an active control group that played a computer game (n=20). Both groups performed three 25-min training sessions per week for five weeks. Pretest-posttest comparisons showed that the training group significantly improved their performance as compared to the active controls, but this was limited to the trained task. In line with our hypothesis, P2-N2-P3 complex showed changes from pre- to posttest. In the training group this was observed as decreased load-effect while in the control group there was an opposite pattern at some latencies. Slow waves elicited during the maintenance were decreased in the easy task and increased in the difficult task. Taken together, our findings suggest that the early and late ERPs are differentially affected by training. When task demands are high, training may lead to an improved ability to actively maintain several stimuli in memory, and when they are low, training results in more efficient processing and automatization.
This article was published in the following journal.
Name: Neurobiology of learning and memory
This study analyzed the mechanisms involved in possible transfer effects for two different working memory updating (WMU) training programs administered to young adults and based on two updating paradi...
The P3b is an extensively studied neurophysiological phenomenon that is predominantly explained in the cognitive neuroscience literature as reflecting context updating, presumably in working memory (W...
The current study investigated how children's working memory updating processes influence arithmetic performance and strategy use. Large samples of third and fourth graders were asked to find estimate...
Two studies using event-related potentials (ERPs) combined with emotional versions of 2-back tasks were performed to examine the effects of negative context on working memory (WM) updating task perfor...
To evaluate the feasibility and acceptability of computerized working memory training in pediatric brain tumor survivors (PBTS) with cognitive deficits, as well as computerized working memory training...
The aim of the iPARK-study is to investigate the effects of a process-based cognitive training program with focus on working memory in patients with Parkinson's Disease (PD). The study is ...
Previous studies indicated that children with attention-deficit/hyperactivity disorder (ADHD) often suffer from deficits in executive function, such as attentional control, inhibition, and...
PTSD is characterized by recurrent intrusion of trauma-related memories and images that cause significant distress and impairment to the affected individuals. The current project aims to e...
This study is an investigation of the effect of a computer-based working memory training program on memory and language processing in at-risk children (e.g., those with working memory weak...
The purpose of this study is to investigate whether working memory training improves behavioral symptoms, neurocognitive performance, and neural functioning in young children with ADHD.
A late-appearing component of the event-related potential. P300 stands for a positive deflection in the event-related voltage potential at 300 millisecond poststimulus. Its amplitude increases with unpredictable, unlikely, or highly significant stimuli and thereby constitutes an index of mental activity. (From Campbell, Psychiatric Dictionary, 6th ed)
A neuropsychological test designed to assess different memory functions. It may incorporate an optional cognitive exam (Brief Cognitive Status Exam) that helps to assess memory related cognitive function.
Memory related to spatial information.
Type of declarative memory, consisting of personal memory in contrast to general knowledge.
Persons who have acquired academic or specialized training in countries other than that in which they are working. The concept excludes physicians for which FOREIGN MEDICAL GRADUATES is the likely heading.