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Complex Problems Require Ternary Solutions: Another Lesson from SIV Nef.

08:00 EDT 11th September 2019 | BioPortfolio

Summary of "Complex Problems Require Ternary Solutions: Another Lesson from SIV Nef."

In this issue of Cell Host & Microbe, Buffalo et al. describe a cryo-EM structure of SIV Nef complexed with AP-2 and tetherin. The structure helps explain why human tetherin is Nef-resistant and why lentiviruses that successfully emerged in humans (HIV-1 and HIV-2) had to evolve novel anti-tetherin strategies.

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Name: Cell host & microbe
ISSN: 1934-6069
Pages: 299-300

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