Apparent diffusion coefficient: Potential biomarker for complete response after neo-adjuvant chemotherapy in breast cancer.

08:00 EDT 12th September 2019 | BioPortfolio

Summary of "Apparent diffusion coefficient: Potential biomarker for complete response after neo-adjuvant chemotherapy in breast cancer."

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Name: The breast journal
ISSN: 1524-4741


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Medical and Biotech [MESH] Definitions

A diagnostic technique that incorporates the measurement of molecular diffusion (such as water or metabolites) for tissue assessment by MRI. The degree of molecular movement can be measured by changes of apparent diffusion coefficient (ADC) with time, as reflected by tissue microstructure. Diffusion MRI has been used to study BRAIN ISCHEMIA and tumor response to treatment.

The use of diffusion ANISOTROPY data from diffusion magnetic resonance imaging results to construct images based on the direction of the faster diffusing molecules.

A method used to study the lateral movement of MEMBRANE PROTEINS and LIPIDS. A small area of a cell membrane is bleached by laser light and the amount of time necessary for unbleached fluorescent marker-tagged proteins to diffuse back into the bleached site is a measurement of the cell membrane's fluidity. The diffusion coefficient of a protein or lipid in the membrane can be calculated from the data. (From Segen, Current Med Talk, 1995).

The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.

Bacteria that can survive and grow in the complete, or nearly complete absence of oxygen.

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