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Atrial fibrillation increases the risk of cerebrovascular events, being responsible of 15-18% of all strokes. The morphological and functional remodelling of the left atrium caused by atrial fibrillation favours blood stasis and, consequently, stroke risk. Several studies suggest that haemodynamic information on the left atrium and the left atrial appendage may help to better characterize stroke risk. The aim of this study was to develop a personalized computational fluid dynamics model of the left atrium which could clarify the haemodynamic implications of atrial fibrillation on a patient-specific basis. In this paper, we present the developed model and its application to two atrial fibrillation patients as a preliminary advancement towards an optimized stroke risk stratification pipeline.
This article was published in the following journal.
Name: Journal of biomechanical engineering
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A THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.
Restoration of functions to the maximum degree possible in a person or persons suffering from a stroke.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Prospective risk assessment tool aimed at identifying potential risks and their impact in healthcare settings.
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