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Is reliance on an inaccurate genome sequence sabotaging your experiments?

08:00 EDT 12th September 2019 | BioPortfolio

Summary of "Is reliance on an inaccurate genome sequence sabotaging your experiments?"

Advances in genomics have made whole genome studies increasingly feasible across the life sciences. However, new technologies and algorithmic advances do not guarantee flawless genomic sequences or annotation. Bias, errors, and artifacts can enter at any stage of the process from library preparation to annotation. When planning an experiment that utilizes a genome sequence as the basis for the design, there are a few basic checks that, if performed, may better inform the experimental design and ideally help avoid a failed experiment or inconclusive result.

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This article was published in the following journal.

Name: PLoS pathogens
ISSN: 1553-7374
Pages: e1007901

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