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Acellular fish skin matrix on thin-skin graft donor sites: a preliminary study.

08:00 EDT 2nd September 2019 | BioPortfolio

Summary of "Acellular fish skin matrix on thin-skin graft donor sites: a preliminary study."

Surgery for head and neck cancer often requires free flap reconstructions, whose harvesting site often requires a thin-skin graft. Wounds from the thin-skin donor site are comparable to an intermediate or deep second-degree burn. This is uncomfortable and can lead to complications such as a long healing time, local infections and pain. Since they are reproducible, these wounds may serve as a model for an objective assessment of new healing medical devices. The acellular fish skin matrix is a new medical device designed to improve healing quality and time.

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Journal Details

This article was published in the following journal.

Name: Journal of wound care
ISSN: 0969-0700
Pages: 624-628

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Medical and Biotech [MESH] Definitions

Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.

The functions of the skin in the human and animal body. It includes the pigmentation of the skin.

The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.

Skin lumpiness or skin surface dimpling often seen on the thighs, buttocks and abdomen. It is due to protrusion of SUBCUTANEOUS FAT into the DERMIS layer of skin.

An autosomal recessive disorder characterized by glassy degenerative thickening (hyalinosis) of SKIN; MUCOSA; and certain VISCERA. This disorder is caused by mutation in the extracellular matrix protein 1 gene (ECM1). Clinical features include hoarseness and skin eruption due to widespread deposition of HYALIN.

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