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Since adhesive hydrogels showed wide applications ranging from wearable soft materials to medical sealant, more and more attentions have been paid on exploration of novel adhesive hydrogels. However, the un-easily removed residue caused by the excessive adhesive strength and sluggish degradation or non-degradation behaviors of the adhesive have always been challenges. Inspired from the multiple complementary hydrogen bonds interactions in DNA, the bio-inspired nucleobase (A, T and U) monomers were firstly synthesized, and used to tackify polyphosphoester hydrogels. The multiple hydrogen bonds and hydrophobic interactions between purine rings and pyrimidine functionalities endowed the hydrogels with excellent controllable adhesive properties. Besides of this, it has been found that these nucleobase tackified hydrogels could be easily peeled off with no residue left, and could be totally degraded under the alkaline condition due to the hydrolysis of phosphoester chains. At the same time, they also exhibited controllable biodegradation to different extent under the different pH conditions. The excellent adhesive performance, controllable biodegradation, and excellent biocompatibility showed by this nucleobase tackified polyphosphoester adhesive hydrogel demonstrated its great potential in wound dressing, tissue sealant and so on.
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The mechanical and biodegradable properties of hydrogels are two essential properties for practical biomaterial applications. In this work, a series of biodegradable polyurethane (PU) hydrogels were s...
In order to replace conventional sutures in wound closing applications, favorable hydrogels with strong wet tissue adhesion and biocompatibility have attracted considerable attention. Herein, inspired...
A new biodegradable, renewable, and environmentally friendly starch-based adhesive for wood-based panels was synthesized. The synthesis was conducted by grafting polymerization of vinyl acetate (VAC) ...
Bone regeneration is still one of the greatest challenges for the treatment of bone defects since no current clinical approach has been proven effective. To develop an alternative biodegradable bone g...
Infection is a major obstacle to wound healing. To enhance the healing of infected wounds, dressings with antibacterial activities and multifunctional properties to promote wound healing are highly de...
This study aims to evaluate the clinical effectiveness of contemporary resin-based adhesive systems by retention rate of resin restorations placed in non carious cervical lesions with four...
The aim of this prospective, randomized study is to compare the efficacy and safety of biodegradable polymer based limus-eluting stents (BPDES) with permanent polymer based everolimus elut...
The objective of the study is to assess the superiority of the biodegradable polymer based limus-eluting stents (ISAR G2, Nobori®) compared with the permanent polymer based everolimus-elu...
The adhesion of the new adhesive strips is investigated on healthy volunteers
To evaluate the impact of a high strength lysine-based adhesive (TissuGlu® Surgical Adhesive) on complications and revision rates in large flap surgery for decubitus repair.
A tissue adhesive that is applied as a monomer to moist tissue and polymerizes to form a bond. It is slowly biodegradable and used in all kinds of surgery, including dental.
Organic polymeric materials which can be broken down by naturally occurring processes. This includes plastics created from bio-based or petrochemical-based materials.
An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.
Dressings comprised of a self-adhesive matrix to which hydrophilic absorbent particles are embedded. The particles consist of CELLULOSE derivatives; calcium ALGINATES; PECTINS; or GELS. The utility is based on providing a moist environment for WOUND HEALING.
The book composed of writings generally accepted by Christians as inspired by God and of divine authority. (Webster, 3d ed)
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...
Complementary and Alternative Medicine
Alternative medicine are whole medical systems that did not fit with conventional medicine as they have completely different philosophies and ideas on the causes of disease, methods of diagnosis and approaches to treatment. Although often overlapping, co...
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...