Topics

Detecting Alcohol-Induced Brain Damage Noninvasively Using Diffusion Tensor Imaging.

08:00 EDT 12th September 2019 | BioPortfolio

Summary of "Detecting Alcohol-Induced Brain Damage Noninvasively Using Diffusion Tensor Imaging."

While alcohol's detrimental effects on the brain are widely acknowledged, diagnostic markers for detection and monitoring alcohol-induced brain damage are lacking. A recent study showed that diffusion tensor imaging can be used to monitor this damage and characterized the progression of the observed changes into early abstinence. Here, we discuss the main findings of that study and highlight current technical limitations which, once addressed, can pave the way to the development of new powerful diagnostic markers for alcohol-induced brain damage.

Affiliation

Journal Details

This article was published in the following journal.

Name: ACS chemical neuroscience
ISSN: 1948-7193
Pages:

Links

DeepDyve research library

PubMed Articles [22297 Associated PubMed Articles listed on BioPortfolio]

Microstructural White Matter Alterations in Men With Alcohol Use Disorder and Rats With Excessive Alcohol Consumption During Early Abstinence.

Although the detrimental effects of alcohol on the brain are widely acknowledged, observed structural changes are highly heterogeneous, and diagnostic markers for characterizing alcohol-induced brain ...

The Water Diffusion of Brain Following Hypoglycemia in Rats-A Study with Diffusion Weighted Imaging and Neuropathologic Analysis.

We established hypoglycemic rat models and divided them into three groups (the sham group, the acute hypoglycemia group and the recovery group). The brain water diffusion was examined using DWI. There...

Brain region specific glucagon-like peptide-1 receptors regulate alcohol-induced behaviors in rodents.

Glucagon-like peptide 1 (GLP-1), an incretin hormone that reduces food intake, was recently established as a novel regulator of alcohol-mediated behaviors. Clinically available analogues pass freely i...

The effects of histone deacetylase inhibitors on the attentional set-shifting task performance of alcohol-dependent rats.

Alcohol dependence causes extensive damage to the central nervous system, resulting in impaired brain structure and behavioral changes. Moreover, histone deacetylase (HDAC) inhibitors restrain the act...

Asymmetric neonatal spasms as an early sign of brain malformation potentially caused by regular light alcohol consumption during the first 22 weeks of pregnancy, a clinical case report.

Introduction: Epileptic spasms are seizures usually associated with a severe developmental epilepsy syndrome with onset in the first year of life, peaking between 3 and 10 months of age [12]. A variet...

Clinical Trials [11293 Associated Clinical Trials listed on BioPortfolio]

PET-based Evaluation of Chemotherapy-induced Brain Damage in Lymphoma

Positron emission tomography (PET) with 18-fluoro-deoxy-glucose (PET-FDG) is emerging as a promising approach for detecting brain lesions in dementia, among which Alzheimer's disease has b...

VR Assessment for Alcohol Related Brain Damage

Pilot study where 10 alcohol-related brain damage (ARBD) patients will undergo a 30-minutes-long cognitive assessment session using the Validation Gate task to evaluate usability of this t...

Efficacy and Safety of Nerve Growth Factor or Edaravone on Alcohol-induced Brain Injury

Alcohol is one of most common harmful substance, and alcohol intake brings great burden on health worldwide. Excess alcohol intake may lead to alcohol-related brain injuries and cognitive ...

Efficacy of Modified Constraint-induced Movement Therapy in Children With Brain Damage

This research centers on the comparison of the immediate efficacy (right after therapy) and the maintained efficacy (3 months and 6 months) between those who receive "Modified Constraint-I...

Noninvasive Assessment of Neuronal Damage by MRI Sodium ( 23Na ) in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the central and peripheral motor neurons, characterized by the rapidity of its evolution (median survival of 3 ...

Medical and Biotech [MESH] Definitions

A diagnostic technique that incorporates the measurement of molecular diffusion (such as water or metabolites) for tissue assessment by MRI. The degree of molecular movement can be measured by changes of apparent diffusion coefficient (ADC) with time, as reflected by tissue microstructure. Diffusion MRI has been used to study BRAIN ISCHEMIA and tumor response to treatment.

A group of mental disorders associated with organic brain damage and caused by poisoning from alcohol.

A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.

Disorders stemming from the misuse and abuse of alcohol.

Acute and chronic neurologic disorders associated with the various neurologic effects of ETHANOL. Primary sites of injury include the brain and peripheral nerves.

Quick Search


DeepDyve research library

Searches Linking to this Article