High expression of PRKDC promotes breast cancer cell growth via p38 MAPK signaling and is associated with poor survival.

08:00 EDT 12th September 2019 | BioPortfolio

Summary of "High expression of PRKDC promotes breast cancer cell growth via p38 MAPK signaling and is associated with poor survival."

DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC), a key component of the DNA damage repair pathway, is associated with chemotherapy resistance and tumor progression.


Journal Details

This article was published in the following journal.

Name: Molecular genetics & genomic medicine
ISSN: 2324-9269
Pages: e908


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Medical and Biotech [MESH] Definitions

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

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