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Predicting Heart Failure After TIPS: Still More Questions Than Answers.

08:00 EDT 13th September 2019 | BioPortfolio

Summary of "Predicting Heart Failure After TIPS: Still More Questions Than Answers."

The transjugular intrahepatic portosystemic shunt (TIPS) is a percutaneous imaging-guided procedure that effectively reduces portal pressure by diverting blood from the portal to the systemic circulation. Despite being a very effective treatment for portal hypertension-related complications, the use of TIPS was hampered for many years by the high rate of TIPS dysfunction, an issue that has become almost anecdotal since the introduction of covered stents. (1)(1) Currently, development of post-TIPS hepatic encephalopathy and, much less frequently, post-TIPS liver and cardiac failure remain as the major complications of TIPS, limiting its use. Until effective preventive and/or therapeutic strategies are available, adequate patient selection is the best existing approach to diminish the rate of these TIPS complications.

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Name: Hepatology (Baltimore, Md.)
ISSN: 1527-3350
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Medical and Biotech [MESH] Definitions

A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Heart failure caused by abnormal myocardial contraction during SYSTOLE leading to defective cardiac emptying.

Heart failure caused by abnormal myocardial relaxation during DIASTOLE leading to defective cardiac filling.

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).

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