Gene dysregulation in peripheral blood of moyamoya disease and comparison with other vascular disorders.

08:00 EDT 18th September 2019 | BioPortfolio

Summary of "Gene dysregulation in peripheral blood of moyamoya disease and comparison with other vascular disorders."

Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease with unknown etiology, sharing many similar clinical symptoms with other vascular disorders. This study aimed to investigate gene dysregulation in peripheral blood of MMD and compare it with other vascular disorders.


Journal Details

This article was published in the following journal.

Name: PloS one
ISSN: 1932-6203
Pages: e0221811


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Medical and Biotech [MESH] Definitions


A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.

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Hematopoietic stem cells found in peripheral blood circulation.

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