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Treatment with carvedilol improves survival of patients with acute-on-chronic liver failure: a randomized controlled trial.

08:00 EDT 20th September 2019 | BioPortfolio

Summary of "Treatment with carvedilol improves survival of patients with acute-on-chronic liver failure: a randomized controlled trial."

In addition to the portal pressure reducing effect, non-selective beta blockers (NSBBs) have possible immunomodulatory and effect in reducing bacterial translocation. Recently, it has been shown that patients who are already on NSBBs should be continued on them (if feasible), if acute-on-chronic liver failure (ACLF) develops. It, however, remains unknown if patients with ACLF and no or small esophageal varices at presentation will benefit from the use of NSBBs. We studied the efficacy and safety of carvedilol in patients with ACLF in reducing mortality, variceal bleeding and non-bleeding complications.

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Name: Hepatology international
ISSN: 1936-0541
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