A Gunn rat model of preterm hyperbilirubinemia.

08:00 EDT 2nd October 2019 | BioPortfolio

Summary of "A Gunn rat model of preterm hyperbilirubinemia."

The impact of bilirubin in preterm infants is poorly understood. An animal model would assist in improving understanding. The Gunn rat lacks uridine diphosphate-glucuronylsyl transferase 1 and can be made acutely hyperbilirubinemic by injection of sulfodimethoxine (sulfa), a drug that displaces bilirubin from albumin and thus increases free bilirubin.


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This article was published in the following journal.

Name: Pediatric research
ISSN: 1530-0447


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