Molecular Basis Underlying Host Immunity Subversion by PE/PPE Family Molecules.

08:00 EDT 3rd October 2019 | BioPortfolio

Summary of "Molecular Basis Underlying Host Immunity Subversion by PE/PPE Family Molecules."

proline-glutamic acid (PE)/proline-proline-glutamic acid (PPE) family proteins, with >160 members, are crucial for virulence, cell wall, host cell fate, host Th1/Th2 balance, and CD8 T cell recognition. Ca signaling is involved in PE/PPE protein-mediated host-pathogen interaction. PE/PPE proteins also function in heme utilization and nitric oxide production. PE/PPE family proteins are intensively pursued as diagnosis biomarkers and vaccine components.


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This article was published in the following journal.

Name: DNA and cell biology
ISSN: 1557-7430


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