Thiophenol detection using an AIE fluorescent probe through self-assembly with TPE-based glycoclusters.

08:00 EDT 4th October 2019 | BioPortfolio

Summary of "Thiophenol detection using an AIE fluorescent probe through self-assembly with TPE-based glycoclusters."

We describe a novel green-emitting tetraphenylethylene-dicyanomethylene-4H-pyran (TPE-DCM) based fluorescent probe (TD-1). Conjugating TPE and DCM moieties allowed TD-1 to display high selectivity for thiophenol with excellent AIE properties in aqueous solution. Nevertheless, the poor water solubility of the hydrophobic structure resulted in a weak and unstable emission intensity. The non-covalent self-assembly of TD-1 with a TPE glycocluster (TPE2S) led to a largely improved water solubility producing a reliable and stable sensing system. The corresponding glyco-probe could sensitively detect exogenous thiophenol concentrations in PBS buffer or environmental water samples.


Journal Details

This article was published in the following journal.

Name: Organic & biomolecular chemistry
ISSN: 1477-0539


DeepDyve research library

PubMed Articles [9127 Associated PubMed Articles listed on BioPortfolio]

A ratiometric fluorescent probe for visualization of thiophenol and its applications.

Thiophenol has a broad application in agriculture and industry. However, thiophenol can harm to the environment and health for its high toxicity. Developing an effective method for detection of thioph...

Discriminative detection of mercury (II) and hydrazine using a dual-function fluorescent probe.

A dual-function fluorescent probe (Probe 1) was developed for discriminative detection of Hg and N H . Probe 1 could discriminatively detect Hg and N H through two different reaction sites, with the m...

A coumarin-fused 'off-on' fluorescent probe for highly selective detection of hydrazine.

Hydrazine is a kind of widely used industrial raw material and a toxic biochemical reagent. Due to its toxic to organisms, hydrazine has been classified to be a hazardous environmental pollutant. It i...

A facile AIE fluorescent probe for broad range of pH detection.

Detection of pH has received more and more attention in various fields. Currently, a hot research topic is focused on how to use a facile fluorescent dye to achieve a wide range and accurate pH detect...

Microwave-Assisted One-Pot Synthesis of Indole-Based Fluorescent Probe for Sensitive Detection of Copper (II).

In this study, a rapid, inexpensive and convenient microwave assisted synthesis of indole-3-propionic acid-bisphenol A diglycidyl ether (IPA-SR3) fluorescent probe was developed. This fluorescent prob...

Clinical Trials [3005 Associated Clinical Trials listed on BioPortfolio]

Clinical Investigation to Evaluate the Haemonetics POLFA Modified Sample Needle Assembly With Vacuum Tube Holder

This study evaluates whether whole blood transferred through the new POLFA needle assembly meets supernatant hemoglobin acceptability standards.

Per-operating Use of a Probe for Detection of β+

The objective of the study is to evaluate the sensibility of the probe Forimtech to detect β+ emission in vivo in humans and its usefulness during elective surgical procedure Hypothesis:T...

Cathepsin Activatable Fluorescent Probe

Real-time detection of cancer cells during surgical removal of a tumor is important. Currently when tissue is removed at the time of surgery, the removed tissue goes to pathology when the ...

Probe Melting Technology for Rapid Detection of Drug Resistant Tuberculosis

Background: Drug resistant tuberculosis is a serious public health problem that threatens the health of human life and the development of society and economy. At present, the diagnosis of...

Doppler Ultrasound Probe for Blood Flow Detection in Severe Upper Gastrointestinal Hemorrhage

The main purpose of this study is to compare outcomes of patients with similar medical conditions, one group managed and treated by current standards (i.e. endoscopic observation(s) and th...

Medical and Biotech [MESH] Definitions

Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.

A form of fluorescent antibody technique utilizing a fluorochrome conjugated to an antibody, which is added directly to a tissue or cell suspension for the detection of a specific antigen. (Bennington, Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)

A molecular probe technique that utilizes branched DNA (bDNA) as a means to amplify the hybridization signal. One end of the bDNA molecule is designed to bind a specific target, while the other end of the bDNA molecule contains many branches of DNA that are designed to bind a probe used for signal detection.

A 20-carbon dibenz(de,kl)anthracene that can be viewed as a naphthalene fused to a phenalene or as dinaphthalene. It is used as fluorescent lipid probe in the cytochemistry of membranes and is a polycyclic hydrocarbon pollutant in soil and water. Derivatives may be carcinogenic.

A nonfluorescent reagent for the detection of primary amines, peptides and proteins. The reaction products are highly fluorescent.

Quick Search

DeepDyve research library

Searches Linking to this Article