Topics

Haemostatic radiotherapy for bleeding cancers of the upper gastrointestinal tract.

08:00 EDT 2nd October 2019 | BioPortfolio

Summary of "Haemostatic radiotherapy for bleeding cancers of the upper gastrointestinal tract."

Bleeding can cause significant morbidity in patients with upper gastrointestinal malignancies. Palliative radiotherapy can palliate bleeding effectively across numerous cancer sites such as the lung and rectum. The data available regarding the role in bleeding from upper gastrointestinal cancers are limited to a single meta-analysis, a phase 2 trial, eleven retrospective cohorts and two case reports, with the majority focusing on gastric cancer. From the data available radiotherapy appears to be a well-tolerated, effective haemostatic agent that should be considered in all patients with bleeding from an upper gastrointestinal malignancy. Questions remain regarding the radiobiology of haemostasis and the optimum fractionation schedule. There is no convincing evidence that protracted higher dose regimens provide additional benefit. Commonly used fractionation schedules use 1, 5 or 10 fractions. Short fractionation schedules have been used in patients with deteriorating performance status.

Affiliation

Journal Details

This article was published in the following journal.

Name: British journal of hospital medicine (London, England : 2005)
ISSN: 1750-8460
Pages: 579-583

Links

DeepDyve research library

PubMed Articles [8407 Associated PubMed Articles listed on BioPortfolio]

Gastrointestinal bleeding in Iceland and in broader terms - a review.

Gastrointestinal bleeding is a common cause for presentation in the emergency room and hospitalization. The bleeding is usually categorized to upper or lower gastrointestinal bleeding. The purpose of ...

The effect of vitamin D levels on gastrointestinal bleeding in patients with warfarin therapy.

: Upper tract gastrointestinal system (GIS) bleeding is considered as an important cause of morbidity and mortality despite modern and advanced endoscopic interventions. In patients with thrombotic st...

Optimal and endoscopic management of upper gastrointestinal bleeding.

Upper gastrointestinal bleeding is an urgent entity associated with a high mortality of about 10 %. Its urgent management includes medical interventions such as volume repletion, blood transfusions,...

Dysphagia prevalence and predictors in cancers outside the head, neck, and upper gastrointestinal tract.

Dysphagia is usually associated with malignancies of the head, neck, and upper gastrointestinal tract, but also occurs in those with tumours outside anatomic swallow regions. It can lead to aspiration...

Catastrophic Gastrointestinal Bleeding: Always Consider Meckel's Diverticulum.

Meckel's diverticulum, a congenital malformation of the gastrointestinal tract, is asymptomatic in the majority of patients but can be associated with some complications. Gastrointestinal bleeding is ...

Clinical Trials [8136 Associated Clinical Trials listed on BioPortfolio]

Direct Discharge of Patients With Upper Gastrointestinal Bleeding From the Emergency Department After Endoscopy

Acute upper gastrointestinal bleeding (UGIB) is a common cause for attendance to the Emergency Department with a wide range of clinical severity, ranging from insignificant to life-threate...

A Pilot and Feasibility Study to Evaluate Capsule Endoscopy

This study is aimed at assessing the capability of the PillCam Platform using the PillCam ESO 2 Capsule in: - Determining whether there is 1) active bleeding in the Upper gastrointesti...

Efficacy of Hemostatic Powder, Endo-ClotTM in the Endoscopic Treatment of Acute Upper Gastrointestinal Bleeding

Acute upper gastrointestinal hemorrhage (UGIH) is a common condition that leads to hospital admission, and has significant associated morbidity and mortality, especially in the elderly. Th...

Study of Incidence of Drug-induced Upper Gastrointestinal Bleeding

The purpose of this study is to determine and analyse the incidence, severity, risk factors and routine management of acute drug-induced upper gastrointestinal bleeding (UGIB) in the popul...

Evaluation of Prognostic Scores in Patients With Upper Gastrointestinal Bleeding and Cancer

This is a prospective and observational study to evaluate oncologic patients that presented upper gastrointestinal bleeding with the use of some prognostic scores.

Medical and Biotech [MESH] Definitions

Vomiting of blood that is either fresh bright red, or older "coffee-ground" in character. It generally indicates bleeding of the UPPER GASTROINTESTINAL TRACT.

The segment of GASTROINTESTINAL TRACT that includes the ESOPHAGUS; the STOMACH; and the DUODENUM.

Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

Inherited disorders that are characterized by subcutaneous and submucosal EDEMA in the upper RESPIRATORY TRACT and GASTROINTESTINAL TRACT.

Transfer of GASTROINTESTINAL MICROBIOTA from one individual to another by infusion of donor FECES to the upper or lower GASTROINTESTINAL TRACT of the recipient.

Quick Search


DeepDyve research library

Relevant Topics

Palliative Care
Palliative care is the active holistic care of patients with advanced progressive illness. Management of pain and other symptoms and provision of psychological, social and spiritual support is paramount. The goal of palliative care is achievement of the ...

Cancer Disease
Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start - for example, cancer that begins in the colon is called colon cancer; cancer th...

Pulmonary
Pulmonary relating to or associated with the lungs eg Asthma, chronic bronchitis, emphysema, COPD, Cystic Fibrosis, Influenza,  Lung Cancer, Pneumonia, Pulmonary Arterial Hypertension, Sleep Disorders etc Follow and track Lung Cancer News ...


Searches Linking to this Article