Titanium Dioxide and Zinc Oxide Nanoparticles in Sunscreens: A Review of Toxicological Data.

07:03 LMT 1st January 0000 | BioPortfolio

Summary of "Titanium Dioxide and Zinc Oxide Nanoparticles in Sunscreens: A Review of Toxicological Data."

The positive effects of sunlight have been known for many years, and the negative ones, too. Sunscreens are physical and chemical UV absorbers. Nanotechnology has developed nanoparticles of physical blockers: titanium dioxide (TiO) and zinc oxide (ZnO). Their smaller diameter and increased bioreactivity are the focus of many toxicological studies. The usage of sunscreens has increased around the world, so all toxicological aspects should be carefully considered. There are and studies: studies on animal and human skin; investigations of potential genotoxicity and cytotoxicity; generation of reactive oxygen species; penetration; skin irritation; acute, subchronic, and chronic toxicity; and carcinogenesis. The experimental conditions of these studies differ from study to study, but most authors agree that there is no penetration of nanoparticles into viable skin layers. Risk-benefit analysis of TiO and ZnO nanoparticles (NPs) usage in sunscreens strongly indicates that potential risks are vastly outweighed over the benefits. Because of the results of some authors indicating possible penetration through damaged skin, further studies should be conducted, primarily addressed on skin penetration mechanisms.


Journal Details

This article was published in the following journal.

Name: Journal of cosmetic science
ISSN: 1525-7886
Pages: 223-234


DeepDyve research library

PubMed Articles [17339 Associated PubMed Articles listed on BioPortfolio]

Titanium dioxide nanoparticles induce apoptosis by interfering with EGFR signaling in human breast cancer cells.

Titanium dioxide nanoparticles, due to their smaller size and increased surface area comparted to the bulk form, are known to be bioreactive and have unexpected toxicological outcomes. Previous studie...

Evaluation of cytogenotoxicity and oxidative stress parameters in male Swiss mice co-exposed to titanium dioxide and zinc oxide nanoparticles.

A number of studies have investigated the adverse toxic effects of titanium dioxide (TiO) nanoparticles (NPs) or zinc oxide (ZnO) NPs. Information on the potential genotoxic effects of the interaction...

A sol-gel method for applying nanosized antibacterial particles to the surface of textile materials in an ultrasonic field.

To prevent possible spread of nosocomial infections - HAI (Healthcare Acquired Infections) in healthcare facilities, Antibacterial textiles are developed. This carried out study has been conducted to ...

Neurotoxicity mediated by oxidative stress caused by titanium dioxide nanoparticles in human neuroblastoma (SH-SY5Y) cells.

Titanium is widely used in biomedicine. Due to biotribocorrosion, titanium dioxide (TiO) nanoparticles (NPs) can be released from the titanium implant surface, enter the systemic circulation, and migr...

Light scattering effect of polyvinyl-alcohol/titanium dioxide nanofibers in the dye-sensitized solar cell.

In the present work, polyvinyl-alcohol/titanium dioxide (PVA/TiO) nanofibers are utilized as a light scattering layer (LSL) on top of the TiO nanoparticles photoanode. The TiO nanoparticles decorated ...

Clinical Trials [2534 Associated Clinical Trials listed on BioPortfolio]

Mycological Comparative Study on Maxillary Dentures of Two Different Materials

Cross over design the investigator divide participants to two groups group (A) will receive rapid heat cured denture base material and group (b) will receive the acrylic denture modified b...

Measurement of the Biting Force of Rabid Heat Cured Acrylic Resin Versus Modified Conventional Acrylic

The purpose of this study is to compare the effect of rapid heat cured acrylic resin material with titanium dioxide nanoparticles added to conventional acrylic resin material on the biting...

Placebo Controlled Trial of a Titanium Dioxide Semiconductor Toothbrush on Mild-to-moderate Gum Disease

The effects on indices of gingivitis/periodontitis will differ between study arms in which the titanium dioxide semiconductor toothbrush is used, compared to an otherwise identical toothbr...

A Study of Efficacy of Zinc Oxide Nanoparticles Coated Socks in Prevention of Unpleasant Foot Odor

This study aimed to study the efficacy of zinc oxide nanoparticles coated socks in prevention of unpleasant foot odor

The Anti-microbial Effect of Titanium Dioxide Nano Particles in Complete Dentures Made for Edentulous Patients

Although cleaning dentures by immersion in chemical denture cleaning solutions is effective in reducing the number of bacteria, a large number remains adhering to the denture surface. Thus...

Medical and Biotech [MESH] Definitions

Iron (II,III) oxide (Fe3O4). It is a black ore of IRON that forms opaque crystals and exerts strong magnetism. The NANOPARTICLES; and MICROSPHERES of its mineral form, magnetite, have many biomedical applications.

Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.

Synthesis, metabolism, and poisoning associated with drugs, pharmaceuticals, and other active molecules. Toxicological phenomena also include the adverse effects of physical phenomena such as RADIATION and NOISE.

Review of the medical necessity of hospital or other health facility admissions, upon or within a short time following an admission, and periodic review of services provided during the course of treatment.

The properties and processes of drug, toxin, and poison metabolism, and their interactions and effects on biological systems. Toxicological phenomena also include the adverse effects of physical phenomena such as RADIATION and NOISE.

Quick Search
DeepDyve research library

Relevant Topic

Nanotechnology is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced.  In its original sense, 'nanotechnology' refers to the projected ability to construct items fr...

Searches Linking to this Article