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Deficits of White Matter Axial Diffusivity in Bipolar Disorder Relative to Major Depressive Disorder: No Relationship to Cerebral Perfusion or Body Mass Index.

08:00 EDT 11th October 2019 | BioPortfolio

Summary of "Deficits of White Matter Axial Diffusivity in Bipolar Disorder Relative to Major Depressive Disorder: No Relationship to Cerebral Perfusion or Body Mass Index."

To compare white matter integrity (WMI) in bipolar disorder (BD) relative to healthy volunteers (HV) and major depressive disorder (MDD). To determine the relationship of bipolar specific differences in WMI to cerebral perfusion, body mass index (BMI) and blood pressure as indices of cardiovascular function.

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Name: Bipolar disorders
ISSN: 1399-5618
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Medical and Biotech [MESH] Definitions

An aphasia characterized by impairment of expressive language (speech, writing, signs) and relative preservation of receptive language abilities (i.e., comprehension). This condition is caused by lesions of the motor association cortex in the frontal lobe (Broca's area and adjacent cortical and white matter regions). The deficits range from almost complete muteness to a reduction in the fluency and rate of speech. CEREBROVASCULAR ACCIDENTS (in particular INFARCTION, MIDDLE CEREBRAL ARTERY) are a relatively common cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp478-9)

A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.

Striped gray and white matter consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the thalamus in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The white matter is the internal capsule.

The region of CENTRAL NERVOUS SYSTEM that appears lighter in color than the other type, GRAY MATTER. It mainly consists of MYELINATED NERVE FIBERS and contains few neuronal cell bodies or DENDRITES.

A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

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