Topics

Photodegradation of bis(1H-tetrazol-5-yl)amine (HBTA), a high nitrogen content tetrazole-based energetic compound in water.

08:00 EDT 30th September 2019 | BioPortfolio

Summary of "Photodegradation of bis(1H-tetrazol-5-yl)amine (HBTA), a high nitrogen content tetrazole-based energetic compound in water."

Tetrazoles have wide industrial applications, notably in the pharmaceutical industry. Tetrazole derivatives such as bis(1H-tetrazol-5-yl)amine (HBTA) have recently been considered by the defense industry as high nitrogen composite propellants. Photodegradation studies under solar simulating conditions showed that HBTA was partially degraded in water, while it was completely degraded under UV light at 254 nm. When HBTA (0.35 mM) was irradiated with simulated sunlight at pH 3.65, there was a 1-day lag phase before the chemical started to degrade, reaching 43.5% degradation after 7 d. However, when pH increased to 5.76, it degraded without lag phase, suggesting that an HBTA anion was involved in the initial degradation of the chemical. 5-Aminotetrazole (5-AT) was identified as a final degradation product and N-(1H-tetrazol-5-yl)formamide(T(5 yl)FA) and 1H-tetrazol-5-ylcarbamic acid (T(5 yl)CA) as intermediate products. At λ = 254 nm, HBTA disappeared rapidly, resulting in the loss of 94% after 65 min. 5-AT was detected together with several transient products including N-(1H-tetrazol-5-yl)carbamohydrazonic acid (T(5 yl)CHA) and T(5 yl)FA. Kinetic studies and products analysis revealed that HBTA photodegraded via two initial routes. One route (a) marked by the initial loss of HN and another (b) marked by the initial loss of N Route a) was characteristics for irradiation with simulated sunlight; however, routes a) and b) proceeded simultaneously under UV light. 5-AT eventually degraded to presumably give N and/or HN under UV light. Understanding the photodegradation pathway of HBTA under simulated sunlight can help in providing the basis for natural attenuation assessment of the chemical in contaminated aquatic environments.

Affiliation

Journal Details

This article was published in the following journal.

Name: Chemosphere
ISSN: 1879-1298
Pages: 125008

Links

DeepDyve research library

PubMed Articles [18035 Associated PubMed Articles listed on BioPortfolio]

Freshness Evaluation in Chub Mackerel ( Scomber japonicus) Using Near-Infrared Spectroscopy Determination of the Cadaverine Content.

We analyzed the volatile basic nitrogen content, pH, total viable cell count, and biogenic amine contents in chub mackerel ( Scomber japonicus) stored at 5 and 25°C to examine changes in freshness. A...

Design, synthesis and biological evaluation of N-(3-(1H-tetrazol-1-yl)phenyl)isonicotinamide derivatives as novel xanthine oxidase inhibitors.

In our previous study, we reported a series of N-phenylisonicotinamide derivatives as novel xanthine oxidase (XO) inhibitors and identified N-(3-cyano-4-((2-cyanobenzyl)oxy)phenyl)isonicotinamide (com...

Transformation products of fluoxetine formed by photodegradation in water and biodegradation in zebrafish embryos (Danio rerio).

The present study investigates the transformation of the antidepressant fluoxetine (FLX) by photo and biodegradation and shows similarities and differences in transformation products (TPs). TPs were i...

Targeting the subpocket in xanthine oxidase: Design, synthesis, and biological evaluation of 2-4-alkoxy-3-(1H-tetrazol-1-yl) phenyl-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives.

Xanthine oxidase is an important target for the treatment of hyperuricemia, gout and other related diseases. Analysis of the high-resolution structure of xanthine oxidase with febuxostat identified th...

Tetrazole hybrids with potential anticancer activity.

Cancer is one of the main causes of death throughout the world. The anticancer agents are indispensable for the treatment of various cancers, but most of them currently on the market are not specific,...

Clinical Trials [4458 Associated Clinical Trials listed on BioPortfolio]

Cryogenic Preservation of Spermatozoa

The reference technique for the conservation of gametes is storage in liquid nitrogen but new vats of nitrogen vapor (storage over liquid nitrogen) or in dry phase (storage in an insulated...

Reaching Protein Target With SmofKabiven® Extra Nitrogen vs Olimel N9E During the Early Phase of Acute Critical Illness

The main focus of the study is to show that SmofKabiven® extra Nitrogen, in a realistic clinical setting, enables to meet high protein requirements in patients during the first week after...

Effects of High vs. Standard Protein Intake in Newborn Extreme Premature

Introduction: The preterm newborn of extremely low birth weight (PNELW), endures adverse nutritional conditions to mimic intrauterine growth. It´s known that amino acids contribute to pr...

PET Biomarkers in Treatment Resistant Depression

The primary objectives of the study are to test whether brain Mono Amine Oxidase-A (MAO-A) levels are elevated in patients with treatment-resistant major depression, and to explore whether...

The Impact of Low Calorie and Low Nitrogen Parenteral Nutrition Support on the Clinical Outcome of Postoperative Patients

The study is designed to investigate the influence of parenteral nutrition (PN) with low nitrogen and calorie supply on the clinical outcome of patients after an operation compared to that...

Medical and Biotech [MESH] Definitions

The urea concentration of the blood stated in terms of nitrogen content. Serum (plasma) urea nitrogen is approximately 12% higher than blood urea nitrogen concentration because of the greater protein content of red blood cells. Increases in blood or serum urea nitrogen are referred to as azotemia and may have prerenal, renal, or postrenal causes. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)

Enzymes that catalyze the cleavage of a carbon-nitrogen bond by means other than hydrolysis or oxidation. Subclasses are the AMMONIA-LYASES, the AMIDINE-LYASES, the amine-lyases, and other carbon-nitrogen lyases. EC 4.3.

Cell surface proteins that bind biogenic amines with high affinity and regulate intracellular signals which influence the behavior of cells. Biogenic amine is a chemically imprecise term which, by convention, includes the catecholamines epinephrine, norepinephrine, and dopamine, the indoleamine serotonin, the imidazolamine histamine, and compounds closely related to each of these.

Ligases that catalyze the joining of adjacent AMINO ACIDS by the formation of carbon-nitrogen bonds between their carboxylic acid groups and amine groups.

A diet that consists mainly of foods with a high content of protein and limited amounts of CARBOHYDRATES.

Quick Search


DeepDyve research library

Searches Linking to this Article