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Clinical pearl: topical timolol for refractory hypergranulation.

08:00 EDT 1st August 2019 | BioPortfolio

Summary of "Clinical pearl: topical timolol for refractory hypergranulation."

Hypergranulation is a frequent complication of dermatologic surgery. Management of postoperative hypergranulation with routine wound care and/or topical silver nitrate often is effective, but refractory cases can be challenging given the paucity of treatment options. We present an alternative treatment of refractory hypergranulation using timolol ophthalmic gel forming solution.

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This article was published in the following journal.

Name: Cutis
ISSN: 2326-6929
Pages: 118-119

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Medical and Biotech [MESH] Definitions

A beta-adrenergic antagonist similar in action to PROPRANOLOL. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor.

A pharmaceutical preparation of brimonidine tartrate and timolol maleate. The combined ADRENERGIC ALPHA2 RECEPTOR AGONIST and ADRENERGIC BETA-ANTAGONIST activity of these drugs reduce INTRAOCULAR PRESSURE in GLAUCOMA patients.

Chronic refractory anemia with granulocytopenia, and/or thrombocytopenia. Myeloblasts and progranulocytes constitute 5 to 40 percent of the nucleated marrow cells.

The period of time following the triggering of an ACTION POTENTIAL when the CELL MEMBRANE has changed to an unexcitable state and is gradually restored to the resting (excitable) state. During the absolute refractory period no other stimulus can trigger a response. This is followed by the relative refractory period during which the cell gradually becomes more excitable and the stronger impulse that is required to illicit a response gradually lessens to that required during the resting state.

Fluorides, usually in pastes or gels, used for topical application to reduce the incidence of DENTAL CARIES.

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