Effect of albumin mediated clustering on the magnetic behavior of MnFeO nanoparticles: experimental and theoretical modeling study.

08:00 EDT 11th October 2019 | BioPortfolio

Summary of "Effect of albumin mediated clustering on the magnetic behavior of MnFeO nanoparticles: experimental and theoretical modeling study."

Over the last two decades, iron oxide based nanoparticles ferrofluids have attracted significant attention for a wide range of applications. For the successful use of these materials in biotechnology and energy, surface coating and specific functionalization is critical to achieve high dispersibility and colloidal stability of the nanoparticles in the ferrofluids. In view of this, the magnetic behavior of clusters of ultra-small MnFeO nanoparticles covered by bovine serum albumin, which is known as a highly biocompatible and environmentally friendly surfactant, is investigated by magnetization measurements, and numerical simulations at an atomic and mesoscopic scale. The coating process with albumin produces a change in the structure, actual size and shape distribution of clusters of exchange coupled particles, giving rise to a distribution of blocking temperatures. The coated system exhibits a superspin glass (SSG) behavior with the SSG freezing temperatures similar to the uncoated ones, providing evidence that the strength of the dipolar interactions is not affected by the presence of the albumin. The DFT calculations show that the albumin coating reduces the surface anisotropy and the saturation magnetization in the nanoparticles leading to lower values of the coercive field in agreement with the experimental findings. Our results clearly demonstrate that the albumin coated clusters of MnFeO particles are ideal systems for energy and biomedical applications since colloidal and thermal stability as well as biosafety is obtained through the albumin coating.


Journal Details

This article was published in the following journal.

Name: Nanotechnology
ISSN: 1361-6528
Pages: 025707


DeepDyve research library

PubMed Articles [26596 Associated PubMed Articles listed on BioPortfolio]

Albumin Coating Prevents Cardiac Effect of the Magnetic Nanoparticles.

We have showed that surface layer can determine cardiac effects of the magnetic nanoparticles (MNPs). Considering the high binding capacity of albumin and low side-effects, the aim of this study was t...

MnFeO nanoparticles accelerate the clearance of mutant huntingtin selectively through ubiquitin-proteasome system.

Neurodegenerative disorders such as Huntington's disease (HD) are fundamentally caused by accumulation of misfolded aggregate-prone proteins. Previous investigations have shown that these toxic protei...

Mn-Doping level dependence on the magnetic response of MnFeO ferrite nanoparticles.

Manganese/iron ferrite nanoparticles with different Mn2+/3+ doping grades have been prepared by a thermal decomposition optimized approach so as to ascertain the doping effect on magnetic properties a...

Removal of chromium(VI) by MnFeO and ferrous ion: synergetic effects and reaction mechanism.

MnFeO was a magnetic material that can be used to adsorb contaminants in the wastewater. Fe(II) could act as a reductant to transfer Cr(VI) into Cr(III). In this paper, mesoporous MnFeO prepared by th...

Critical behavior of ensembles of superparamagnetic nanoparticles with dispersions of magnetic parameters.

Different processes governing magnetic properties of an ensemble of magnetic nanoparticles in the temperature region close to a transition from superparamagnetic to paramagnetic state are analyzed and...

Clinical Trials [8224 Associated Clinical Trials listed on BioPortfolio]

Topical Silver Nanoparticles for Microbial Activity

Silver nanoparticles are one of most nanoparticles use nowadays in the research area because it has specific physical and chemical properties, in medical fields silver nanoparticles can in...

Intraperitoneal Aerosolisation of Albumin-stabilized Paclitaxel Nanoparticles for Recurrent GI and Ovarian Cancer

The PIPAC nab-pac study is designed to examine the safety and efficacy of IV paclitaxel combined with repeated pressurized intraperitoneal aerosol therapy (PIPAC) using albumin bound nanop...

Effect of Albumin Infusion on Oxidative Albumin Modification, Albumin Binding Capacity and Plasma Thiol Status

The aim of this study is to investigate the effect of albumin infusion on oxidative albumin modification, on plasma thiol status and on albumin binding capacity for DS in patients who rout...

Topical Application of Silver Nanoparticles and Oral Pathogens in Ill Patients

The purpose of this study is to determine whether oral topic silver nanoparticles are effective to reduce potential pathogen microbial loads in mechanical ventilation patients.

a Clinical Study.the Effect of Addition of Insoluble Antibacterial Nanoparticles(IABN) in Resin Base Provisional Cement

The effect of Antibacterial Nanoparticles, Incorporated in cement, on S.mutans in the margins of provisional restorations is going to be examined clinically by using two kinds of provision...

Medical and Biotech [MESH] Definitions

An injectable formulation of albumin-bound paclitaxel NANOPARTICLES.

A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).

Cell surface proteins that bind albumin with high affinity and trigger intracellular changes influencing the behavior of cells.

Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.

Animal behavior associated with the nest; includes construction, effects of size and material; behavior of the adult during the nesting period and the effect of the nest on the behavior of the young.

Quick Search

DeepDyve research library

Relevant Topics

Biotechnology - Biotech
"using living things to create products or to do tasks for humans" About Biotechnology - Biotech Biotechnology is the practice of using plants, animals and micro-organisms such as bacteria, as well as biological processes - such as the ripen...

Collaborations in biotechnology
Commercial and academic collaborations are used throughout the biotechnology and pharmaceutical sector to enhance research and product development. Collaborations can take the form of research and evaluation agreements, licensing, partnerships etc. ...

Searches Linking to this Article