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Studies using time-frequency analysis have reported that somatosensory evoked potentials provide information regarding the location of spinal cord injury. However, a better understanding of the time-frequency components derived from somatosensory evoked potentials is essential for developing more reliable algorithms that can diagnosis level (location) of cervical injury. In the present study, we proposed a random forests machine learning approach, for separating somatosensory evoked potentials depending on spinal cord state. For data acquisition, we established rat models of compression spinal cord injury at the C4, C5, and C6 levels to induce cervical myelopathy. After making the compression injury, we collected somatosensory evoked potentials and extracted their time-frequency components. We then used the random forests classification system to analyze the evoked potential dataset that was obtained from the three groups of model rats. Evaluation of the classifier performance revealed an overall classification accuracy of 84.72%, confirming that the random forests method was able to separate the time-frequency components of somatosensory evoked potentials from rats under different conditions. Features of the time-frequency components contained information that could identify the location of the cervical spinal cord injury, demonstrating the potential benefits of using time-frequency components of somatosensory evoked potentials to diagnose the level of cervical injury in cervical myelopathy.
This article was published in the following journal.
To identify and reveal the sensitivity and efficiency of dynamic somatosensory evoked potentials (DSSEPs) in the diagnosis of cervical spondylotic myelopathy (CSM).
Multimodal neurological prognostication is recommended for comatose patients after cardiac arrest. The absence of cortical N20-potentials in a somatosensory evoked potential (SSEP) examination reliabl...
Motor learning is associated with plasticity in both motor and somatosensory cortex. It is known from animal studies that tetanic stimulation to each of these areas individually induces long-term pote...
To evaluate and compare the cervical spinal canal (CSC) morphology among healthy people, cervical spondylosis myelopathy (CSM), and latent cervical spondylosis (LCS, people with cervical spine degener...
Cervical spondylotic myelopathy (CSM) is a complex disease that presents with various signs and symptoms of cervical spinal cord impairment that may lead to significant clinical morbidity.
The purpose of this study is to determine if intravenous fosaprepitant can interfere with nervous system monitoring signals in patients having surgery under general anesthesia. This medica...
The relation between burst and suppression periods in transcranial and direct cortical recorded EEG with cortical amplitudes median nerve somatosensory evoked potentials is studied. ...
The purpose of this study is to determine the feasibility of recording evoked compound action potentials (ECAPs) and somatosensory evoked potentials (SSEPs) from the spinal cord (SC) and D...
Cervical myelopathy is common among aging population.One of the complication of cervical myelopathy is balance impairment.In this study, the patients with cervical myelopathy undergo biome...
To evaluate if somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) obtained with electroencephalography (EEG) and electromyography (EMG) can be used to detect changes...
The recorded electrical responses from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported. Often used synonymously to event-related potentials which are associated with higher level cognitive processes.
Somatosensory evoked potentials generated through the application of HEAT to the SKIN with a LASER. They are often used clinically to assess the function of the central nociceptive system and in diagnosing NOCICEPTIVE PAIN.
The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.
The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS.
The electric response evoked in the cerebral cortex by visual stimulation or stimulation of the visual pathways.
Spinal Cord Disorders
The spinal cord is a bundle of nerves that runs down the middle of the back which carry signals back and forth between the body and brain. It is protected by vertebrae, which are the bone disks that make up the spine. An accident that damages the verte...
Mergers & Acquisitions
Commercial and market reports on mergers and acquisitions in the biotechnology, pharmaceutical, medical device and life-science industries. Mergers and acquisitions (abbreviated M&A;) is an aspect of corporate strategy, corporate finance and manageme...