Exploration of Cervical Myelopathy Location from Somatosensory Evoked Potentials Using Random Forests Classification.

08:00 EDT 10th October 2019 | BioPortfolio

Summary of "Exploration of Cervical Myelopathy Location from Somatosensory Evoked Potentials Using Random Forests Classification."

Studies using time-frequency analysis have reported that somatosensory evoked potentials provide information regarding the location of spinal cord injury. However, a better understanding of the time-frequency components derived from somatosensory evoked potentials is essential for developing more reliable algorithms that can diagnosis level (location) of cervical injury. In the present study, we proposed a random forests machine learning approach, for separating somatosensory evoked potentials depending on spinal cord state. For data acquisition, we established rat models of compression spinal cord injury at the C4, C5, and C6 levels to induce cervical myelopathy. After making the compression injury, we collected somatosensory evoked potentials and extracted their time-frequency components. We then used the random forests classification system to analyze the evoked potential dataset that was obtained from the three groups of model rats. Evaluation of the classifier performance revealed an overall classification accuracy of 84.72%, confirming that the random forests method was able to separate the time-frequency components of somatosensory evoked potentials from rats under different conditions. Features of the time-frequency components contained information that could identify the location of the cervical spinal cord injury, demonstrating the potential benefits of using time-frequency components of somatosensory evoked potentials to diagnose the level of cervical injury in cervical myelopathy.


Journal Details

This article was published in the following journal.

Name: IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
ISSN: 1558-0210


DeepDyve research library

PubMed Articles [5638 Associated PubMed Articles listed on BioPortfolio]

A new diagnostic medium for cervical spondylotic myelopathy: Dynamic somatosensory evoked potentials.

To identify and reveal the sensitivity and efficiency of dynamic somatosensory evoked potentials (DSSEPs) in the diagnosis of cervical spondylotic myelopathy (CSM).

Stratifying comatose postanoxic patients for somatosensory evoked potentials using routine EEG.

Multimodal neurological prognostication is recommended for comatose patients after cardiac arrest. The absence of cortical N20-potentials in a somatosensory evoked potential (SSEP) examination reliabl...

Somatosensory cortical excitability changes precede those in motor cortex during human motor learning.

Motor learning is associated with plasticity in both motor and somatosensory cortex. It is known from animal studies that tetanic stimulation to each of these areas individually induces long-term pote...

Pathological changes of cervical spinal canal in cervical spondylotic myelopathy: A retrospective study on 39 cases.

To evaluate and compare the cervical spinal canal (CSC) morphology among healthy people, cervical spondylosis myelopathy (CSM), and latent cervical spondylosis (LCS, people with cervical spine degener...

Cervical canal stenosis due to cervical spondylotic myelopathy C4-C5: A case report.

Cervical spondylotic myelopathy (CSM) is a complex disease that presents with various signs and symptoms of cervical spinal cord impairment that may lead to significant clinical morbidity.

Clinical Trials [3096 Associated Clinical Trials listed on BioPortfolio]

Effect of Fosaprepitant on Motor Evoked and Somatosensory Evoked Potentials Under General Anesthesia

The purpose of this study is to determine if intravenous fosaprepitant can interfere with nervous system monitoring signals in patients having surgery under general anesthesia. This medica...

SEP Changes During Deep Anesthesia

The relation between burst and suppression periods in transcranial and direct cortical recorded EEG with cortical amplitudes median nerve somatosensory evoked potentials is studied. ...

Measuring Evoked Potentials From the Spinal Cord and Dorsal Root Ganglion

The purpose of this study is to determine the feasibility of recording evoked compound action potentials (ECAPs) and somatosensory evoked potentials (SSEPs) from the spinal cord (SC) and D...

Clinical Evaluation and Rehabilitation System for Dynamic Balance Control in Cervical Myelopathy Patients

Cervical myelopathy is common among aging population.One of the complication of cervical myelopathy is balance impairment.In this study, the patients with cervical myelopathy undergo biome...

A Study to Investigate Evoked Potentials as Markers of Ketamine-induced Cortical Plasticity in Patients With Major Depressive Disorder

To evaluate if somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) obtained with electroencephalography (EEG) and electromyography (EMG) can be used to detect changes...

Medical and Biotech [MESH] Definitions

The recorded electrical responses from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported. Often used synonymously to event-related potentials which are associated with higher level cognitive processes.

Somatosensory evoked potentials generated through the application of HEAT to the SKIN with a LASER. They are often used clinically to assess the function of the central nociceptive system and in diagnosing NOCICEPTIVE PAIN.

The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.

The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS.

The electric response evoked in the cerebral cortex by visual stimulation or stimulation of the visual pathways.

Quick Search

DeepDyve research library

Relevant Topics

Spinal Cord Disorders
The spinal cord is a bundle of nerves that runs down the middle of the back which carry signals back and forth between the body and brain. It is protected by vertebrae, which are the bone disks that make up the spine. An accident that damages the verte...

Mergers & Acquisitions
Commercial and market reports on mergers and acquisitions in the biotechnology, pharmaceutical, medical device and life-science industries. Mergers and acquisitions (abbreviated M&A;) is an aspect of corporate strategy, corporate finance and manageme...

Searches Linking to this Article