Vogt-Koyanagi-Harada Disease following Yellow Fever Vaccination.

08:00 EDT 11th October 2019 | BioPortfolio

Summary of "Vogt-Koyanagi-Harada Disease following Yellow Fever Vaccination."

: To report the manifestation of Vogt-Koyanagi-Harada- disease (VKH) following yellow fever vaccination. : Case report. : A 34-year-old immunocompetent male had tinnitus, headache, and decreased vision after a booster dose of yellow fever vaccine. Visual acuity was 20/100 in the right eye and 20/80 in the left, with serous retinal detachment (SRD) and choroidal thickening identified on clinical examination and multimodal imaging. Lumbar puncture revealed pleocytosis and an increased protein content, but extensive investigations ruled out infectious/neurological diseases. Pulse intravenous methylprednisolone was given, followed by a tapering regimen of high-dose oral prednisone. Azathioprine was started early, 3 weeks after initiation of oral steroids. Intraocular inflammation and SRD rapidly resolved, with visual acuity reaching 20/20 in both eyes, after 3 weeks. No recurrence of intraocular inflammation or sign of depigmentation was so far noticed, at 2 years of follow-up. : Yellow fever vaccine may be a possible trigger for VKH.


Journal Details

This article was published in the following journal.

Name: Ocular immunology and inflammation
ISSN: 1744-5078
Pages: 1-4


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Medical and Biotech [MESH] Definitions

Vaccine used to prevent YELLOW FEVER. It consists of a live attenuated 17D strain of the YELLOW FEVER VIRUS.

An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus.

Group activities directed against VACCINATION.

Rate of VACCINATION as defined by GEOGRAPHY and or DEMOGRAPHY.

Resistance to a disease agent resulting from the production of specific antibodies by the host, either after exposure to the disease or after vaccination.

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