Topics

Early Adaptive CD4+ T cell Immunity in Atherosclerosis goes Local.

08:00 EDT 11th October 2019 | BioPortfolio

Summary of "Early Adaptive CD4+ T cell Immunity in Atherosclerosis goes Local."

No Summary Available

Affiliation

Journal Details

This article was published in the following journal.

Name: Cardiovascular research
ISSN: 1755-3245
Pages:

Links

DeepDyve research library

PubMed Articles [28082 Associated PubMed Articles listed on BioPortfolio]

The aorta can act as a site of naïve CD4+ T cell priming.

Aortic adaptive immunity plays a role in atherosclerosis; however, the precise mechanisms leading to T cell activation in the arterial wall remain poorly understood.

When rubber meets the road: how innate features of adaptive immune cells play critical roles in transplant alloimmunity.

Studies on adaptive cells have largely focused on features that are specific to adaptive immunity. However, adaptive cells utilize innate cell features to modulate their responses, and this area of T ...

Persisting enteropathy and disturbed adaptive mucosal immunity due to MHC class II deficiency.

Intestinal epithelial cells (IECs) form a fundamental mucosal barrier and actively participate in tolerance and immunity against intestinal contents. Major histocompatibility complex class II (MHC II)...

A murine model of the effects of inhaled CuO nanoparticles on cells of innate and adaptive immunity - a kinetic study of a continuous three-month exposure.

The inhalation or application of nanoparticles (NPs) has serious impacts on immunological reactivity. However, the effects of NPs on the immune system are influenced by numerous factors, which cause a...

Lysophosphatidic acid decreased macrophage foam cell migration correlated with downregulation of fucosyltransferase 8 via HNF1α.

Aberrant fucosylation, such as α-1,6 fucosylation catalyzed by fucosyltransferase 8 (Fut8), is associated with reduced cell migration and is responsible for cholesterol-enriched foam cell accumulatio...

Clinical Trials [15210 Associated Clinical Trials listed on BioPortfolio]

Adaptive Immune Responses and Repertoire in Influenza Vaccination and Infection (SLVP031)

The purpose of this study is provide a better understanding of the adaptive immune response to the licensed flu vaccines. The investigators hope the information learned from this study wil...

Shrinking Target Adaptive Radiotherapy for Locally Advanced Non-Small Cell Lung Cancer

This study aims to use a type of radiation (adaptive radiotherapy) to deliver curative-intent treatment to patients with non-small cell lung cancer, whose tumors would otherwise be too lar...

The Effect of Statin Treatment on Trained Innate Immunity

The innate immune system plays a pivotal role in the development and progression of atherosclerosis. Recently, it was reported that monocytes can develop a long-lasting immunological memor...

Epigenetic Markers of B-Cell Function in Low Birth Weight Infants

Low birth weight (LBW) status (< 10% for gestational age at birth) is associated with increased risk for diseases such as type II diabetes mellitus, hypertension, chronic obstructive pulmo...

Study of Intracoronary CD34+ Cell Administration in Patients With Early Coronary Atherosclerosis

How safe and effective are CD34+ cell intracoronary injections for treating coronary endothelial dysfunction (CED)?

Medical and Biotech [MESH] Definitions

An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.

Protection from an infectious disease agent that is mediated by B- and T- LYMPHOCYTES following exposure to specific antigen, and characterized by IMMUNOLOGIC MEMORY. It can result from either previous infection with that agent or vaccination (IMMUNITY, ACTIVE), or transfer of antibody or lymphocytes from an immune donor (IMMUNIZATION, PASSIVE).

A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p100 precursor protein and is important for maturation of B-LYMPHOCYTES and adaptive HUMORAL IMMUNITY.

Cytosolic signaling adaptor proteins that were initially discovered by their role in the innate immunity (IMMUNITY, INNATE) response of organisms that lack an adaptive immune system. This class of proteins contains three domains, a C-terminal ligand recognition domain, an N-terminal effector-binding domain, and a centrally located nuclear-binding oligomerization domain. Many members of this class contain a C-terminal leucine rich domain which binds to PEPTIDOGLYCAN on the surface of BACTERIA and plays a role in pathogen resistance.

An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria.

Quick Search


DeepDyve research library

Relevant Topic

Immunology
Allergies Automimmune Disease Human Papillomavirus (HPV) Immunology Vaccine Immunology is the study of immunity and the defence mechanisms of the body. A greater understanding of immunology is needed to develop vaccines, understand ...


Searches Linking to this Article