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Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients.

08:00 EDT 15th October 2019 | BioPortfolio

Summary of "Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients."

The purpose of this study is to determine the mutation frequencies of key driver genes in uveal melanoma (UM) in Chinese patients and to detect associations between metastasis and the mutation of these genes.

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Journal Details

This article was published in the following journal.

Name: Ophthalmic research
ISSN: 1423-0259
Pages: 1-11

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Medical and Biotech [MESH] Definitions

A ring of tissue extending from the scleral spur to the ora serrata of the retina. It consists of the uveal portion and the epithelial portion. The ciliary muscle is in the uveal portion and the ciliary processes are in the epithelial portion.

Tumors or cancer of the UVEA.

Mutations in genes which lead to cell or organism death when occurring in combination with mutations in one or more other genes.

Diseases of the uvea.

Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.

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