Topics

RAPID COMMUNICATION: Dietary tributyrin supplementation and submaximal exercise promote activation of equine satellite cells.

08:00 EDT 20th October 2019 | BioPortfolio

Summary of "RAPID COMMUNICATION: Dietary tributyrin supplementation and submaximal exercise promote activation of equine satellite cells."

Post-exercise skeletal muscle repair is dependent upon the actions of satellite cells (SCs). The signal(s) responsible for activation of these normally quiescent cells in the horse remain unknown. The objective of the experiment was to determine if submaximal exercise or tributyrin (TB) supplementation are sufficient to stimulate SC activation. Adult geldings were fed a control diet (n=6) or a diet containing 0.45% TB (n=6). After 30 d, the geldings performed a single bout of submaximal exercise. Middle gluteal muscle biopsies and blood were collected on d -1, 1 , 3 and 5 relative to exercise. Diet had no effect on any parameter of physical performance. Total RNA isolated from the gluteal muscle of TB fed geldings contained greater (P < 0.05) amounts of myogenin mRNA than controls. Satellite cell isolates from TB supplemented horses had a greater (P = 0.02) percentage of proliferating cell nuclear antigen immunopositive (PCNA+) SC than controls after 48 h in culture. Submaximal exercise was sufficient to increase (P < 0.05) the percentage of PCNA(+) cells in all isolates obtained during recovery period. No change in the amount of gluteal muscle Pax7 mRNA, a lineage marker of satellite cells, occurred in response to either diet or exercise. Our results indicate that both submaximal exercise and TB prime SCs for activation and cell cycle reentry but are insufficient to cause an increase in Pax7 expression during the recovery period.

Affiliation

Journal Details

This article was published in the following journal.

Name: Journal of animal science
ISSN: 1525-3163
Pages:

Links

DeepDyve research library

PubMed Articles [11507 Associated PubMed Articles listed on BioPortfolio]

Impaired Heart Rate Variability, Valsalva and 30:15 Ratio Indexes Are Associated With Reduced Submaximal Exercise Capacity in Subjects With Diabetes Mellitus.

To assess cardiac autonomic control and its association with submaximal exercise measured using the 6-minute walk test (6MWT) in subjects with type-2 diabetes mellitus (DM2).

Effect of exercise and butyrate supplementation on microbiota composition and lipid metabolism.

The composition and activity of the gut microbiota depend on the host genome, nutrition, and life-style. Exercise and sodium butyrate (NaB) exert metabolic benefits in both mice and humans. However, t...

Protein Supplementation Does Not Augment Adaptations to Endurance Exercise Training.

Recently, it has been speculated that protein supplementation may further augment the adaptations to chronic endurance exercise training. We assessed the effect of protein supplementation during chron...

PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training.

Impaired mitochondrial function has been implicated in the pathogenesis of age-associated metabolic diseases through regulation of cellular redox balance. Exercise training is known to promote mitocho...

Isoflavone did not promote additional effects on heart rate variability of post-menopausal women submitted to combined exercise training: A clinical, controlled, randomized, double-blind study.

The aim of the study is to investigate the effects of ingesting isoflavones associated with combined aerobic and resistance exercise training on heart rate variability (HRV) indices in postmenopausal ...

Clinical Trials [11744 Associated Clinical Trials listed on BioPortfolio]

Effects Oxygen Supplementation Determined Better Exercise Capacity in Eisenmenger Syndrome

The purpose of this study was to evaluate the acute effects of oxygen supplementation during a submaximal exercise test in patients with Eisenmenger's Syndrome.

HMB Supplementation in Addition to Multicomponent Exercise in Old Adults

Evidence supports the fact that multicomponent exercise and β-hydroxy-β-methylbutyrate (HMB) supplementation are, separately, effective in improving old adult's health and palliate funct...

The Effect of Probiotics on GI Symptoms

A double-blind randomized, placebo-controlled study will be performed with experienced endurance athletes to assess the effect of probiotics supplementation on the composition and function...

Ergogenic and Antioxidant Effects of Corinthian Currant

The purpose of the present study is to investigate the effect of pre-exercise supplementation of Corinthian currant on metabolism, performance and blood redox status during, and after an a...

Effects of L-arginine and L-citrulline Supplementation on Muscle Respiration

The objective of this trial is to determine the effects of dietary supplementation with the amino acids, L-arginine and L-citrulline, on endurance performance and mitochondrial respiration...

Medical and Biotech [MESH] Definitions

Controlled physical activity, more strenuous than at rest, which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used. The intensity of exercise is often graded, using criteria such as rate of work done, oxygen consumption, and heart rate.

A state arrived at through prolonged and strong contraction of a muscle. Studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. Muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.

Dietary recommendations that promote reduction in or prevention of high blood pressure. Recommendations include increasing intake of fruits and vegetables, and high-fiber, low-fat foods and reducing the intake of DIETARY SODIUM and high fat foods.

The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an EXERCISE TEST.

Methods or programs of physical activities which can be used to promote, maintain, or restore the physical and physiological well-being of an individual.

Quick Search


DeepDyve research library

Relevant Topic

Rheumatology
Arthritis Fibromyalgia Gout Lupus Rheumatic Rheumatology is the medical specialty concerned with the diagnosis and management of disease involving joints, tendons, muscles, ligaments and associated structures (Oxford Medical Diction...


Searches Linking to this Article