Elevated cholesteryl ester transfer protein activity early in pregnancy predicts prediabetes 5 years later.

08:00 EDT 29th October 2019 | BioPortfolio

Summary of "Elevated cholesteryl ester transfer protein activity early in pregnancy predicts prediabetes 5 years later."

Cholesteryl ester transfer protein (CETP) regulates high density lipoproteins (HDL)-cholesterol levels and interaction between glucose and HDL metabolism is central in the development of diabetes.


Journal Details

This article was published in the following journal.

Name: The Journal of clinical endocrinology and metabolism
ISSN: 1945-7197


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Medical and Biotech [MESH] Definitions

Round-shaped structure usually located in the upper fundus of the UTERUS in early pregnancy. It comprises EMBRYO; AMNIOTIC FLUID; and YOLK SAC. It is visible in PRENATAL ULTRASONOGRAPHY by the fifth week of pregnancy. Its size is often used to determine and monitor GESTATIONAL AGE; FETAL GROWTH; and PREGNANCY COMPLICATIONS.

The first alpha-globulins to appear in mammalian sera during development of the embryo and the dominant serum proteins in early embryonic life. They reappear in the adult serum during certain pathologic states, primarily hepatocellular carcinoma. They may also be elevated in the amniotic fluid and maternal serum during pregnancy in ANENCEPHALY.

A superfamily of large integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE characterized by accumulation of cholesteryl ester in various tissues.

A lipocalin that is the most abundant protein synthesized and secreted by the ENDOMETRIUM from mid-LUTEAL PHASE of the MENSTRUAL CYCLE through early PREGNANCY.

A sub-class of protein tyrosine phosphatases that contain an additional phosphatase activity which cleaves phosphate ester bonds on SERINE or THREONINE residues that are located on the same protein.

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