Radiosynthesis and preclinical evaluation of CCimbi-701 - Towards the imaging of cerebral 5-HT receptors.

08:00 EDT 31st October 2019 | BioPortfolio

Summary of "Radiosynthesis and preclinical evaluation of CCimbi-701 - Towards the imaging of cerebral 5-HT receptors."

The serotonin 7 (5-HT ) receptor is suggested to be involved in a broad variety of CNS disorders, but very few in vivo tools exist to study this important target. olecular imaging with positron emission tomography (PET) would enable an in vivo characterization of the 5-HT receptor. However, no clinical PET radiotracer exists for this receptor and thus we aimed to develop such a tracer. In this study, we present the preclinical evaluation of [ C]Cimbi-701.


Journal Details

This article was published in the following journal.

Name: Journal of labelled compounds & radiopharmaceuticals
ISSN: 1099-1344


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