CXCR3 from chemokine receptor family correlates with immune infiltration and predicts poor survival in osteosarcoma.

08:00 EDT 15th October 2019 | BioPortfolio

Summary of "CXCR3 from chemokine receptor family correlates with immune infiltration and predicts poor survival in osteosarcoma."

Chemokine receptors have a crucial role in regulating tumor mediating immunity and also implicated in the prognosis of some cancers. Here, the association between CXC chemokine receptors (CXCR2-5) and prognosis in osteosarcoma was studied.


Journal Details

This article was published in the following journal.

Name: Bioscience reports
ISSN: 1573-4935


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Medical and Biotech [MESH] Definitions

An INTEFERON-inducible CXC chemokine that is specific for the CXCR3 RECEPTOR.

A CXC chemokine that is induced by GAMMA-INTERFERON and is chemotactic for MONOCYTES and T-LYMPHOCYTES. It has specificity for the CXCR3 RECEPTOR.

A CXC chemokine that is induced by GAMMA-INTERFERON. It is a chemotactic factor for activated T-LYMPHOCYTES and has specificity for the CXCR3 RECEPTOR.

CXCR receptors that are expressed on the surface of a number of cell types, including T-LYMPHOCYTES; NK CELLS; DENDRITIC CELLS; and a subset of B-LYMPHOCYTES. The receptors are activated by CHEMOKINE CXCL9; CHEMOKINE CXCL10; and CHEMOKINE CXCL11.

A CC chemokine with specificity for CCR5 RECEPTORS. It is a chemoattractant for NK CELLS; MONOCYTES and a variety of other immune cells. This chemokine is encoded by multiple genes.

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