Role of surface charge in enhancing antibacterial activity of fluorescent carbon dots.

07:00 EST 8th November 2019 | BioPortfolio

Summary of "Role of surface charge in enhancing antibacterial activity of fluorescent carbon dots."

Herein, different surface charged Carbon dots (Cdots) were synthesized by using diethylene glycol as a carbon source with various amine containing surface passivating agents. The synthesis method is very simple and fast microwave oven based, that results in almost similar sized positive, negative and uncharged fluorescent Cdots which has been confirmed by zeta potential analysis in our case. The formation of Cdots was confirmed by characterization using fluorescence spectroscopy, transmission electron microscopy (TEM), XRD, FT-IR, and XPS spectroscopy. To find out relative bactericidal activity of these Cdots, green fluorescence protein (GFP) expressing recombinant E.coli bacteria were taken as a model system. Time dependent bacterial growth and FACS study demonstrated that both uncharged Cdots and positively charged Cdots were showing better bactericidal activity as compared to negative charged Cdots. The Cdots caused elevation of reactive oxygen species (ROS) level, which is possibly leading to bacterial cell death.


Journal Details

This article was published in the following journal.

Name: Nanotechnology
ISSN: 1361-6528


DeepDyve research library

PubMed Articles [31347 Associated PubMed Articles listed on BioPortfolio]

2D Graphdiyne Oxide Serves as a Superior New Generation of Antibacterial Agents.

Graphdiyne (GDY) as an emerging 2D carbon-network nanomaterial possesses many fascinating properties that lead to numerous exciting applications, but the use of GDY and its derivatives in the antibact...

Photoelectrochemical Solar water splitting: the role of the carbon nano materials in bismuth vanadate composite photoanodes towards efficient charge separation and transport.

Photoelectrochemical performance of bismuth vanadate (BiVO4) photoanode is limited by poor charge separation and transport properties. The role of carbon nanotube, reduced graphene oxide or graphitic ...

Synergistic antibacterial activity of silver nanoparticles and hydrogen peroxide.

The increasing challenge of antibiotic resistance requires not only the discovery of new antibiotics, but also the development of new alternative approaches. Herein, the synergistic antibacterial acti...

Ultrathin g-CN with enriched surface carbon vacancies enables highly efficient photocatalytic nitrogen fixation.

An ultra-thin carbon nitride with loose structure and more carbon defects on the surface was achieved through high-temperature peeling methods. Its composition, morphological characteristics, surface ...

Antibacterial photodynamic activity of carbon quantum dots/polydimethylsiloxane nanocomposites against Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae.

Despite of great researcher's efforts the design of antibacterial surfaces is still a big challenge due to appearance of mutated bacteria strains resistant to antibiotics. In this work, results of str...

Clinical Trials [8586 Associated Clinical Trials listed on BioPortfolio]

Antibacterial Activity of Urea Against Ocular Bacteria

Antibacterial properties of urea was tested against 35 isolates from ocular infections.

Phase 3 Multicenter Randomized Double Blind Placebo Controlled Study With Antibacterial Prophylaxis in Azacitidine Treated MDS Patients

Infections are a major and prevalent life-threatening complication among patients with myelodysplastic syndrome (MDS). Currently, the role of prophylactic antibacterial agents after chemot...

Increasing Exercise Adherence After Percutaneous Coronary Intervention With the Fitbit Charge HR Device

Design: Single center, prospective, randomized study that will compare activity levels in patients who complete cardiac rehabilitation after clinically indicated percutaneous coronary inte...

Physical Activity Monitored by Fitbit Charge 2 in Improving Quality of Life in Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

This phase II trial studies how well physical activity monitored by Fitbit Charge 2 works in improving quality of life in participants with ovarian, primary peritoneal, or fallopian tube c...

Validation of Two Wrist-worn Devices for the Assessment of Energy Expenditure in Cardiac Patients.

Improving physical activity is a core component of secondary prevention and cardiac (tele)rehabilitation. Commercially available activity trackers are frequently used to monitor and promot...

Medical and Biotech [MESH] Definitions

An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.

Reducing the SURFACE TENSION at a liquid/solid interface by the application of an electric current across the interface thereby enhancing the WETTABILITY of the surface.

A tumor necrosis family receptor with specificity for OX40 LIGAND. It is found on the surface of activated T-LYMPHOCYTES where it plays a role in enhancing cytokine production and proliferation of CD4-POSITIVE T-LYMPHOCYTES. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.

The natural bactericidal property of BLOOD due to normally occurring antibacterial substances such as beta lysin, leukin, etc. This activity needs to be distinguished from the bactericidal activity contained in a patient's serum as a result of antimicrobial therapy, which is measured by a SERUM BACTERICIDAL TEST.

Quick Search

DeepDyve research library

Relevant Topics

Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...

Recombinant DNA
Recombinant DNA is the formation of a novel DNA sequence by the formation of two DNA strands. These are taken from two different organisms. These recombinant DNA molecules can be made with recombinant DNA technology. The procedure is to cut the DNA of ...

Searches Linking to this Article