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Application of multiple MLL gene rearrangement detection techniques for children with acute mononuclear leukemia.

07:00 EST 10th November 2019 | BioPortfolio

Summary of "Application of multiple MLL gene rearrangement detection techniques for children with acute mononuclear leukemia."

To assess the value of detecting multiple rearrangements of MLL gene in children with acute mononuclear leukemia (AML).

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Journal Details

This article was published in the following journal.

Name: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
ISSN: 1003-9406
Pages: 1077-1080

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Medical and Biotech [MESH] Definitions

DNA sequences, in cells of the T-lymphocyte lineage, that code for T-cell receptors. The TcR genes are formed by somatic rearrangement (see GENE REARRANGEMENT, T-LYMPHOCYTE and its children) of germline gene segments, and resemble Ig genes in their mechanisms of diversity generation and expression.

Ordered rearrangement of T-cell variable gene regions coding for the antigen receptors.

The ordered rearrangement of gene regions by DNA recombination such as that which occurs normally during development.

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Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.

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