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Pd(0)-Catalyzed Cyclizative Carboboration of -Iodo-1,6-diene ( = 1 or 2): Access to Structurally Complex Allylboronates and Alkylboronates.

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Summary of "Pd(0)-Catalyzed Cyclizative Carboboration of -Iodo-1,6-diene ( = 1 or 2): Access to Structurally Complex Allylboronates and Alkylboronates."

A Pd(0)-catalyzed cyclizative carboboration reaction of -iodo-1,6-diene ( = 1, 2) with Bpin has been developed. When 1-iodo-1,6-diene was employed as the substrate, a process of intramolecular 6,6-alkenylboration was achieved to deliver 6-membered cyclic allylborate. On the other hand, 2-iodo-1,6-diene was found to proceed via 2-cyclopropanation/1-boration, thus affording a (bicyclo[3.1.0]hexan-1-ylmethyl)borate product.

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Name: Organic letters
ISSN: 1523-7052
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