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BAGSE: A Bayesian Hierarchical Model Approach for Gene Set Enrichment Analysis.

07:00 EST 8th November 2019 | BioPortfolio

Summary of "BAGSE: A Bayesian Hierarchical Model Approach for Gene Set Enrichment Analysis."

Gene set enrichment analysis has been shown to be effective in identifying relevant biological pathways underlying complex diseases. Existing approaches lack the ability to quantify the enrichment levels accurately, hence preventing the enrichment information to be further utilized in both upstream and downstream analyses. A modernized and rigorous approach for gene set enrichment analysis that emphasizes both hypothesis testing and enrichment estimation is much needed.

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Name: Bioinformatics (Oxford, England)
ISSN: 1367-4811
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