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Topographical patterning has recently attracted lots of attention in regulating cell fate, understanding the mechanism of cell-microenvironment interactions, and solving the great issues of regenerative medicine. The introduced patterns offer topographical cues that can affect the reconstruction of the cytoskeleton or stimulate cell membrane receptors. Numerous studies have focused on these effects on cell behavior including attachment, migration, proliferation, and differentiation. In this review, five aspects of topographical patterning are discussed: (1) the process of typical micro-/nanotechniques and their advantages and limitations; (2) the effects of patterning on the mechanical properties and surface properties of substrates; (3) the influences of micro-/nanopatterns on the behavior of mesenchymal stem cells, as well as the underlying mechanisms; (4) the application of patterns to solve the issues of targeted organs (e.g., skin, nerves, blood vessels, bones, and heart). In the end, future perspectives that would help promote the efficiency of topographical patterning are proposed.
This article was published in the following journal.
Name: Journal of materials chemistry. B
Considering object identification and recognition as well as human interaction with objects, texture as a surface property plays a crucial role. A deeper understanding of tactile aesthetics can be use...
Ultrasound is an advanced non-thermal food-processing technology that has received increasing amounts of interest as an alternative to, or an adjuvant method for, conventional processing techniques. T...
Scanning probe lithography is used to directly pattern monolayer transition metal dichalcogenides (TMDs) without the use of a sacrificial resist. Using an atomic-force microscope, a negatively biased ...
Materials with surface wrinkles at a micro/nanoscale possess extraordinary fascinating properties, and various techniques have been employed to create controllable wrinkles. Herein, natural polysaccha...
In this paper I postulate that the processing of concepts which are deemed controllable is rooted in neurological machinery located in the posterior parietal cortex specialised for the processing of o...
To examine the relationships of obesity and fat patterning with morbidity and mortality in Black Americans.
This study aims to evaluate the effectiveness of 4D image acquisition and post-processing with Vios Works for the evaluation of 3D images acquired on GE Magnetic Resonance Imaging scanners...
The current project will examine the impact of an emotional processing intervention on emotional processing abilities in a sample of 50 persons with moderate to severe TBI. Outcome will be...
Work in our group has revealed that short-term (7-day) administration of antidepressants produces positive biases in the processing of emotional information in healthy volunteers. Such eff...
We propose to assess one method of sperm selection based on the characteristics of spermatozoa recently introduced: Sperm Selection Assay, which used a gradient of concentration of progest...
The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.
Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
Computer processing of a language with rules that reflect and describe current usage rather than prescribed usage.
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
Those characteristics that distinguish one SEX from the other. The primary sex characteristics are the OVARIES and TESTES and their related hormones. Secondary sex characteristics are those which are masculine or feminine but not directly related to reproduction.
Track and monitor developments in stem cell research and commercial development. Follow the tabs above to read the latest global news, research, clinical trials on stem cells and follow companies active in the stem cell industry. BioPort...