Increased risk of eczema after joint replacement: A population-based retrospective cohort study.

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Summary of "Increased risk of eczema after joint replacement: A population-based retrospective cohort study."

There are very few reports of eczema and other prosthetic-related allergic skin complications following arthroplasty. We aimed to assess the risk of eczema after joint replacement.We performed a retrospective population-based cohort study in 2024 joint replacement patients using the Longitudinal Health Insurance Database. For comparison, 8096 controls were selected, with 4 control subjects for each joint replacement patient matched for age, sex, and index year, to assess eczema risk. We examined 14-year cumulative eczema incidence associated with age, sex, immunity, disease history, and joint replacement location.Eczema rates in the joint replacement patients were 38% higher than in the control group (57.90 vs 41.84 per 1000 person-years, respectively). Compared with the control group, joint replacement patients showed a 1.35-fold increased risk of eczema according to the multivariable Cox model (95% Confidence interval [CI] = 1.23-1.49). Knee replacement patients had higher eczema risk compared with the control group (Hazard ratio [HR] = 1.45, 95% CI = 1.33-1.70). Stratified by study period, the joint replacement cohort had a higher eczema risk after the 3-month follow-up.Our study revealed that joint arthroplasty increased risk of eczema in this 14-year follow-up study, and this was not related to personal atopic history or gender.


Journal Details

This article was published in the following journal.

Name: Medicine
ISSN: 1536-5964
Pages: e17914


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Medical and Biotech [MESH] Definitions

Partial or total replacement of a joint.

Replacement of the hip joint.

A partial joint replacement in which only one surface of the joint is replaced with a PROSTHESIS.

Partial or total replacement of one or more FINGERS, or a FINGER JOINT.

Replacement of the ELBOW JOINT.

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