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Cancer is increasingly becoming the major cause leading to death in many countries, and digestive system malignant tumours account for the majority of cancer incidence and mortality. Metabolism has been identified as a core hallmark of cancer. Peroxisome proliferator activated receptor gamma coactivator alpha (PGC-1α) is a pivotal regulator of mitochondrial energy metabolism. Accumulating evidence reveals that PGC-1α is essential in cancer development.
This article was published in the following journal.
Name: Anti-cancer agents in medicinal chemistry
The WHO Classification of Digestive System Tumours presented in the first volume of the WHO Classification of Tumours series' fifth edition reflects important advancements in our understanding of tumo...
The malignant tumors including oral cancer, colorectal cancer, pancreatic cancer, and esophageal cancer, of the digestive system are a common high-fatal malignancy. Porphyromonas gingivalis, as the mo...
Patients with central nervous system germ cell tumours (CNS-GCTs) commonly initially present to primary care or general paediatricians. Prolonged symptom intervals (SI) are frequently seen in CNS-GCTs...
In recent years, targeted therapy has received widespread attention. Among these therapies, anti-angiogenic targeted drugs have become one of the hotspots of research. Apatinib is a novel oral small m...
The objective of the PRELUDE study is to describe the use of lanreotide Autogel® (LAN ATG) combined with Peptide Receptor Radionuclide Therapy (PRRT) in the treatment of progressive neuro...
To evaluate the tolerance and safety of cinobufacini injection intraperitoneal treatment on digestive system cancer patients with malignant ascites, and propose dosage regimens for future ...
This is an open-label phase II study of an investigational drug, sunitinib malate in patients with advanced malignant paraganglioma or phaeochromocytoma cancer. Paragangliomas (PGs) are tu...
The purpose of this study is to determine whether the combination of Temozolomide and Cisplatinum is effective in the treatment of malignant glial tumours of children and adolescents
This phase II trial studies how well abemaciclib works in treating patients with digestive system neuroendocrine tumors that have spread to other places in the body, do not respond to trea...
An abnormal passage communicating between any components of the digestive system, or between any part of the digestive system and surrounding organ(s).
Properties and processes of the DIGESTIVE SYSTEM and DENTITION as a whole or of any of its parts.
Biological actions and events that constitute the functions of the DIGESTIVE SYSTEM.
Surgery performed on the digestive system or its parts.
Digestive system manifestations of diseases of the gastrointestinal system or of other organs.
Bladder Cancer Brain Cancer Breast Cancer Cancer Cervical Cancer Colorectal Head & Neck Cancers Hodgkin Lymphoma Leukemia Lung Cancer Melanoma Myeloma Ovarian Cancer Pancreatic Cancer ...
Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start - for example, cancer that begins in the colon is called colon cancer; cancer th...