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Synthesis, biological evaluation and molecular docking studies of novel di-hydropyridine analogs as potent antioxidants.

07:00 EST 4th November 2019 | BioPortfolio

Summary of "Synthesis, biological evaluation and molecular docking studies of novel di-hydropyridine analogs as potent antioxidants."

The aim of the present study to synthesis and biological evaluation of 3-ethyl 5-methyl 2-(2-aminoethoxy)-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate derivatives. Dihydropyridine (DHP) is an important class of calcium antagonist structure, the structure of the compound pyridine natured with semi-saturated with two substituents replacing one double bond. DHP inhibits the influx of extracellular Ca2+ through L-type voltage-dependent calcium channels in earlier reports.

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Name: Current topics in medicinal chemistry
ISSN: 1873-4294
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